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research | 13 3 2016 laser For this, a monocentric, prospective, randomised, two-arm, observer-blinded study was initiated, in which the effect of blue laser irradiation is compared with the established IR lasers with a wavelength of 980 nm (approval by the Ethics Committee of the Medical Faculty of the University of Bonn, No. 095/15). As part of these investigations, the clinical healing process after laser-based preprosthetic gin- givectomieswillbeevaluatedonthebasisofanumber of clinical assessment parameters. Among these pa- rameters are bleeding on probing (BOP), sulcus fluid flow rate (SFFR), modified gingiva index (MGI), mod- ified early wound healing index (mEHI) and attach- ment status. The laser parameters for the blue light laserwere2 W,cwand3 W,cwforthe980 nmlaseras thesebothpowersettingsdemonstratedcomparable cutting efficiencies in pre-experiments. An identical handpiece with a 320 μm fibre was used for both la- sers. Figures 10a–c shows examples of a gingivec- tomy after a crown fracture in a multimorbid patient (anti coagulants/diabetes). Figures 11a–d demon- strates the exposureofthemarginalcavitymarginin a patient with extended vestibular caries before root canal treatment. Figure 12 illustrates a comprehen- sivegingivectomyinapatientwithidiopathicgingival hyperplasia. Preliminary results from this study show that no adverse effects occurred either after the use of the 445 nm laser or after the use of the 980 nm laser. Woundhealingwasgoodwithbothlasers.Inallofthe cases that have been treated so far, no pain medica- tion was necessary after the surgery. However, the 445 nm laser showed a higher level of cutting effec- tiveness that led to shorter operation times. Unlike the 980 nm laser, no fibre conditioning is necessary forthe445 nmlaserwavelength.Furthermore,work- inginnon-contactmodeandperiodiccleaningofthe application tip improves the treatment outcome. In particular, it was determined that haemostasis was better with the 445 nm laser. Conclusion The wavelength of 445 nm displays a high level of direct coupling to tissue during incision or excision that is achieved by the favourable biophysical prop- erties of this radiation. Comparison of the cutting ef- fectiveness shows advantage effects with 445 nm in comparison to 980 nm. The consistent results from the histological investigations and the cell culture testsshowthatwithbothlaserstested,damageinthe sense of an unspecific thermal interaction occurs. Therefore, modification of the emission wavelength ofthediodelaserdoesnotshifttheriskofapplication. No disadvantages in comparison to the already es- tablished IR diode lasers were found. Modifying the wavelength thus represents an advancement with clinicalrelevanceregardingadesiredrangeofindica- tions (incision/excision/disinfection)._ Kurz & bündig Der 445 nm-Laser stellt eine innovative Alternative zu den bisher etablierten Diodenlasersystemen dar. Eine ver- besserte Schnittleistung bei geringerem Leistungseinsatz unter Beibehaltung der Vorteile der Anwendung von Dioden- lasern im Rahmen oraltherapeutischer Maßnahmen am Weichgewebe bedeutet eine Weiterentwicklung der Infrarot- systeme, ohne dass Nachteile erkennbar sind. contact Center for Dental, Oral and Maxillofacial Dentistry (Zentrum für ZMK) Bonn/AG Laser in der Zahnheilkunde (Lasers in Dentistry working group) Welschnonnenstraße 17 53111 Bonn, Germany www.amlarebo.uni-bonn.de Fig. 12: Gingivectomy in the lower jaw (idiopathic hyperplasia) using a 445 nm laser (1,5 W, cw, 320 µm Ø) and a 980 nm laser (3 W, cw, 320 µm Ø) in a split-mouth design. Surgical procedure using 445 nm was less time consuming. Literature Fig. 12 32016