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ePaper created 2017-05-12, 09:42:21 | version 1.38.0
| industry Tab. 2: Treated sites/frequencies: (n = 77 in 41 patients) 1st quadrant 2nd quadrant 3rd quadrant 4th quadrant 11 – 2 12 – 4 13 – 1 14 – 6 15 – 3 16 – 4 17 – 4 18 – 2 21 – 5 22 – 2 23 – 3 24 – 7 25 – 4 26 – 5 27 – 4 28 – 0 31 – 0 32 – 0 33 – 0 34 – 1 35 – 2 36 – 5 37 – 3 38 – 0 41 – 1 42 – 0 43 – 0 44 – 2 45 – 1 46 – 5 47 – 1 48 – 0 = 26 (33.77 %) = 30 (38.96 %) = 11 (14.28 %) = 10 (12.99 %) data entry a purely descriptive evaluation was carried out as is usual for studies of this kind. Results Altogether twelve dental practices and dental surgery practices from all over Germany took part. The observation period (from the first treatment day of the first patient to the last treatment day of the last patient) extended from August 2013 to June 2015. It was possible to evaluate recording sheets on 41 patients (19 female, 22 male) aged 22 to 74 years (mean age: 55.2 years, median age: 57 years). Patients with certification of appropriate pre-operative diagnoses or indications were in- cluded in the study. In the process it became appar- ent that CERASORB® Paste was used with very dif- ferent diagnoses in daily routine work: A total of 23 concomitant illnesses in 16 patients were reported. The most frequent were hypertension in six patients, allergic reactions in four patients and tinnitus, rheumatism and Tension Neck Syndrome in two patients each. Four participants were smokers. Six patients were taking nine different medications alto- gether, the most frequent being 100 mg aspirin in three cases. Augmentation or defect filling was carried out at a total of 77 sites in the 41 patients (Table 2). CERASORB® Paste was most often used in 1 ml volumes (n=31 patients [76 %]) (range: 0.5—3.0 ml). In none of the cases was autologous cancellous bone mixed in. Twenty membranes were used in 18 cases (19 resorbable, one non-resorbable). Complete pri- mary wound closure was achieved in 36 cases. Antibiotics were applied in 24 cases (58 %), only pre-operatively in five patients and only postop- eratively in 19 patients. The most frequently-used antibiotics were clindamycin (in 20 patients) and amoxicillin (n = 2). They were taken for a duration of five to ten days, the mean and most frequent duration being ten days. The surgical operations and postoperative periods were free from compli- cations. At the clinical follow-up examination performed one to two weeks after the operation, an evaluation was made of the state of the membranes, the extent of inflammation and patient compliance. The soft-tissue healing was classified as very good or good in 93 % of cases (Table 3). The membrane situ- ation was also classed as very good in 36 % of cases and as good in 51 %. These results were certainly also due to good patient compliance. 26 patients (= 63 %) indicated that they rinsed regularly; this was done by far the most frequently (in 18 cases) with chlorhexidine. It was suggested to the dentists carrying out the treatment that clinical evaluations of the progress and success of new bone formation (by comparison with the initial state on the day of the operation) should be made after about three, six, nine and twelve months. Analysis of the results revealed undis- turbed healing and a continual decrease in the amount of synthetic bone regeneration material Tab. 3: Follow-up examination after one to two weeks Number Very good (1) Good (2) Satisfactory (3) No answer Mean(1–3) 24 (59 %) 14 (34 %) 3 (7 %) 6 (33.3 %) 11 (61.1 %) 0 1 (5.6 %) 1.48 1.64 Evaluation of soft-tissue healing [n=41 patients]: Evaluation of membrane [n=18 patients]: 28 implants 2 2017