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ePaper created 2017-05-12, 09:42:21 | version 1.38.0
| industry Augmentation and defect filling in oral surgery A multicentre non-interventional study Author: Henriette Lerner, Germany Introduction There is considerable demand for bone replace- ment and augmentation materials in the field of dental medicine, especially in oral and maxillofacial surgery. A wide variety of biological and synthetic re- placement materials is now available. In recent years synthetic substances containing calcium and phos- phate have been developed. These require minimal effort, present no practical problems and can be used efficiently and economically. They are usually accepted by the body without problems; their tissue tolerability is excellent and they are neither locally nor systemically toxic. Unlike materials of biological origin they do not pose any risk of infection or sensi- tisation. In all cases it is of course necessary to take into account the individual hard tissue situation at the site at which bone regeneration material is to be used. A product that is easy to apply is especially useful for filling smaller defects; CERASORB® Paste, which has been available for some time, is such a product. Tolerability (n = 41) Fig. 1: Overall assessment of very good tolerability by the dentist carrying good out treatment. satisfactory unsatisfactory no answer 26 implants 2 2017 The aim was to perform a non-interventional study to evaluate its use by as many independent users as possible; handling and usefulness were to be studied in different oral surgical indications under everyday conditions in different dental practices. Material and methodology An account is given of experience with the use of the β-tricalcium phosphate preparation CERASORB® Paste within a multicentre study. It was intended that dental practices throughout Ger- many, independent from one another, participate. Goal and methods were defined in an observation plan to ensure that the procedure was consistent. All results were entered on prepared recording sheets. Because of the non-interventional nature of this study, no particular therapeutic or application plan was imposed; users were instead referred to the instructions given in the information for use. Patients aged between 18 and 70 years with the following pre-operative diagnoses or indications were to be enrolled in the study: – alveolar defect – apicoectomy – preparation of implant bed – post exstirpational cyst filling – internal sinus lift – periodontal pocket – further indications equivalent to those already mentioned Patients were not to be included in the study if they were unsuitable for bone regeneration proce- dures because of general medical exclusion criteria or local inflammation in the surgical area, or if they regularly took medication that could influence wound healing (such as cortisone preparations and immunosuppressants).