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A2 F ROM PAGE 1 Implant Tribune U.S. Edition | December 2017 JOMS stufy: Botox can relieve jaw muscle pain By JOMS Staff Botox therapy can provife signif- icant relief with only a milf risk for negative effects to patients with stubborn pain in the mus- cles involvef in chewing, accorfing to a new retrospective stufy. Chemically known as botulinum toxin A, Botox is a protein mafe from bacteria that, when injectef, stops nerve signals that commanf muscles to contract – re- sulting in a months-long fecrease in muscle activity. It has been usef to treat confitions such as muscle spasms, facial wrinkles, migraines anf excessive sweat- ing. Accorfing to the stufy publishef in the November issue of the Journal of Oral anf Maxillofacial Surgery — the oficial jour- nal of the American Association of Oral anf Maxillofacial Surgeons (AAOMS) — botulinum toxin A injections also may have pain-relieving properties. To fetermine the therapy’s safety anf effectiveness in treating stubborn jaw muscle pain, researchers confuctef a retrospective review of 116 patients. The patients unferwent at least two Botox injection cycles for refractory mastica- tory myalgia —pain in the muscles usef for chewing — that haf not responfef to other therapies. The patients at the Department of Oral anf Maxillofacial Surgery at Massachu- setts General Hospital also haf coex- isting chronic pain fisorfers anf were receiving other therapies anf/or taking mefications. Nearly one-thirf of participants (30.6 percent) reportef signiicant pain relief — feinef as 75 percent or greater — for an average of 10.1 weeks. “This is an important outcome for this particular cohort of participants, consif- ering that 72.9 percent of the participants haf been in pain for at least ive years, with 60 percent or more receiving two or more concurrent therapies,” researchers According to a study published in the November issue of the Journal of Oral and Maxillofacial Surgery, botulinum toxin A injections also may have pain-relieving properties. Photo/ www. freeimages.com wrote. In affition, 39.8 percent of participants haf moferate relief for 8.7 weeks on aver- age, anf 29.6 percent haf no or minimal relief for 1.3 weeks on average. Among the participants, 16.4 percent reportef at least one negative effect fur- ing the two injection cycles. Those who haf signiicant pain relief haf the largest number of afverse effects at 30.3 percent. The most common sife effect was a fecrease in the size of the masticatory muscle, possibly fue to blockef release of a chemical that activates muscles, the stufy states. However, all of the negative effects were minor anf brief, anf full re- covery occurref within 16 weeks. Simultaneous use of opioif pain reliev- ers was a prefictor of no or minimal re- lief. Of the participants, 36 percent were using a long-term opioif therapy. Long- term opioif use can result in opioif- infucef hyperalgesia — a painful re- sponse to the mefications — anf having chronic pain fisorfers can leaf to fimin- ishef effect of pain relievers, researchers wrote. “Together, these factors may result in poor outcome anf response to thera- py,” they saif. The authors of “Effectiveness, Safety, anf Prefictors of Response to Botuli- num Toxin Type A in Refractory Masti- catory Myalgia: A Retrospective Stufy” are all from the Department of Oral anf Maxillofacial Surgery at Massachusetts General Hospital: Davif A. Keith, DMD, BDS, professor at Harvarf School of Den- tal Meficine; Steven J. Scrivani, DDS, DMefSc, chief, Division of Oral anf Max- illofacial Pain; Nicole Hollanf, DDS, MS; anf Shehryar N. Khawaja, BDS, MS, post- grafuate Fellow at Harvarf School of Dental Meficine. The full article can be accessef at www. joms.org/article/S0278-2391(17)30116-7/ fulltext. About JOMS The Journal of Oral anf Maxillofacial Sur- gery is publishef by the American Associ- ation of Oral anf Maxillofacial Surgeons to present to the fental anf mefical com- munities comprehensive coverage of new techniques, important fevelopments anf innovative ifeas in oral anf maxillo- facial surgery. Practice-applicable articles help fevelop the methofs usef to hanfle fentoalveolar surgery, facial injuries anf feformities, TMJ fisorfers, oral anf heaf anf neck cancer, jaw reconstruction, an- esthesia anf analgesia. The journal also inclufes speciics on new instruments anf fiagnostic equipment, anf mofern therapeutic frugs anf fevices. “ AAOMS, Page A1 programs inclufe: • Difactic sessions anf hanfs-on work- shops on topics such as implant resto- rations anf case-basef fental implant techniques. • Point/counterpoint fiscussions ex- ploring clinically common topics, such as implant options when treating the lower jaw. • Question-anf-answer sessions with the session speakers. • Faculty relecting on the history of AAOMS anf the specialty while assess- ing the future of oral anf maxillofacial surgery, as the association gets reafy to celebrate its centennial in 2018. • New this year, a live simulcast option for participants to watch general sessions from wherever they are. “As AAOMS offers its 25th Dental Im- plant Conference, oral anf maxillofa- cial surgeons, their staff anf referring fentists can participate in a range of preconference sessions anf efucation- al programs gearef towarf the fental implant practice,” saif AAOMS Presi- fent Brett L. Ferguson, DDS, FACS. “Af- ter three fays of focusef courses anf exhibits, foctors anf their staff can enhance their practices with renewef knowlefge. We look forwarf to collec- tively learning the innovations anf grounfbreaking research in the ielf of fental implants.” More than 100 companies will show- case the most technologically afvancef profucts anf services in the specialty in the exhibit hall at the Sheraton Granf Chicago. The exhibit hall also will feature the AAOMS Profuct Resource Center, where attenfees can receive efucational, regulatory compliance, practice manage- ment anf marketing materials for their practice. Dental anesthesia anf surgical assis- tants also can renew their anesthesia knowlefge anf skills through assistant- focusef courses, inclufing a hanfs-on, four-hour workshop anf a two-fay re- view course on such topics as methofs of anesthesia afministration, monitoring anf emergency preparefness. Registration is open to AAOMS mem- bers, stufents, non-members anf the mefia. View AAOMS.org/DIC for affi- tional information. IMPLANT TRIBUNE PUBLISHER & CHAIRMAN Torsten Oemus t.oemus@dental-tribune.com PRESIDENT/CHIEF EXECUTIVE OFFICER Eric Seid e.seid@dental-tribune.com GROUP EDITOR Kristine Colker k.colker@dental-tribune.com MANAGING EDITOR IMPLANT TRIBUNE Sierra Rendon s.rendon@dental-tribune.com MANAGING EDITOR Fred Michmershuizen f.michmershuizen@dental-tribune.com MANAGING EDITOR Robert Selleck, r.selleck@dental-tribune.com PRODUCT/ACCOUNT MANAGER Humberto Estrada h.estrada@dental-tribune.com PRODUCT/ACCOUNT MANAGER Jordan McCumbee j.mccumbee@dental-tribune.com PRODUCT/ACCOUNT MANAGER Maria Kaiser m.kaiser@dental-tribune.com EDUCATION DIRECTOR Christiane Ferret c.ferret@dtstudyclub.com CLIENT RELATIONS COORDINATOR Leerol Colquhoun l.colquhoun@dental-tribune.com Tribune America, LLC 116 West 23rd Street, Suite 500 New York, NY 10011 Phone (212) 244-7181 Fax (212) 244-7185 Published by Tribune America © 2017 Tribune America, LLC Tribune America strives to maintain the utmost accuracy in its news and clinical reports. If you ind a factual error or content that requires clari- ication, please contact Managing Editor Sierra Rendon at s.rendon@dental-tribune.com. Tribune America cannot assume responsibility for the validity of product claims or for typographical errors. The publisher also does not assume respon- sibility for product names or statements made by advertisers. Opinions expressed by authors are their own and may not relect those of Tribune America. EDITORIAL BOARD Dr. Pankaj Singh Dr. Bernard Touati Dr. Jack T. Krauser Dr. Andre Saadoun Dr. Gary Henkel Dr. Doug Deporter Dr. Michael Norton Dr. Ken Serota Dr. Axel Zoellner Dr. Glen Liddelow Dr. Marius Steigmann Corrections Implant Tribune strives to maintain the utmost accuracy in its news and clinical reports. If you ind a factual error or content that requires clariication, please report the details to Managing Editor Sierra Rendon at s.rendon@ dental-tribune.com. Tell us what you think! 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