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04 ASIA PACIFIC NEWS Dental Tribune Asia Pacific Edition | 9/2017 Mobile breath analysis device promising for early disease diagnosis By DTI SEOUL, South Korea: Breath pattern recognition was once thought of as a futuristic diagnostic platform. Research in this area has been gain- ing much attention because breath analysis is a non-invasive and low- cost method. Among the most crit- ical challenges in this regard is the development of sufficiently sensi- tive sensors. Korean scientists have now developed high-sensitivity sensors to enable early monitoring of various diseases based on bio- marker gases in breath. The research group, led by Dr Il-Doo Kim in the Department of Materials Science and Engineering at the Korea Advanced Institute of Science and Technology, has devel- oped highly sensitive and selective chemiresistive sensors that can po- tentially diagnose specific diseases by analysing exhaled breath gases. The sensors were developed by combining hollow protein-tem- plated nanocatalysts with electro- m o c . k c o t s r e t t u h s / a v e n o K a r i v l E © Breath analysis can detect trace changes in exhaled breath components, con- tributing to early diagnosis of disease. Breath analysis starts with capturing exhaled breath in a Ted- lar bag and subsequently injecting the captured breath gases into a miniaturised sensor system, simi- lar to an alcohol detector. It is pos- sible to analyse exhaled breath very rapidly with a simple analys- ing process. Breath analysis can detect trace changes in exhaled breath components, contributing to early diagnosis of disease. How- ever, gases in the breath occur at very low levels, from 1 ppb to 1 ppm, and so extremely sensitive sensors are needed for accuracy. In particular, it has been a chal- lenge for chemiresistive chemical sensors to selectively detect spe- cific biomarkers. spun metal oxide nanostructures, which have large and highly po- rous surface areas and thus achieve high sensitivity. Human breath consists of diverse components, including water vapour, hydrogen, acetone, toluene, ammonia, hydrogen sul- phide and carbon monoxide, with greater or lesser amounts exhaled in the case of illness. Some of these are closely associated with diseases such as asthma, lung can- cer, Type 1 diabetes mellitus, and halitosis. Conventionally, platinum and palladium are used in developing the catalysts; however, the sensi- tivity is insufficient. The sensors in the current study were spe- cially optimised for selective detection of specific biomarkers. Their performance was approxi- Study evaluates digital scanners laboratory scanner were used to scan the custom model for both scenarios. Analysis was per- formed using 3-D metrology soft- ware to measure discrepancies be- tween the master model and ex- perimental casts. to According the study, Planmeca PlanScan was found to have the best trueness and preci- searchers looked at seven scan- ners and analysed their perfor- mance based on 3-D comparisons. They found that Planmeca Plan- Scan and 3Shape’s TRIOS per- formed the best. The study’s main objective was to compare the trueness and precision of the scanners in both posterior sextant and complete- arch scenarios. Additionally, it looked at the time each scan re- quired and correlated it with true- ness and precision. To achieve the most accurate and no-bias results, a custom com- plete-arch model was fabricated with a refractive index similar to that of tooth structure. Six digital intraoral scanners and one digital By DTI CHARLESTON, USA: With intra- oral scanning becoming increas- ingly prevalent in dentistry, know- ing which scanner will give the best performance is essential. In a new study led by Dr Walter Renne, from the Department of Oral Re- habilitation at the Medical Uni- versity of South Carolina, re- AD DenTech 25.10 - 28.10.2017 Shanghai / China Self-curing calcium hydroxide paste (cid:149) For indirect pulp capping and linings under dental filling materials (cid:149) Sufficient working time (cid:149) A short setting time in the mouth (cid:149) Bacteriostatic (cid:149) Antimicrobic effect due to a high pH-value (cid:149) Contains 26% calcium hydroxide (cid:149) Preservation of vitality due to pulp recovering mately three to four times better than that of platinum and palla- dium catalyst-loaded nanofibre sensors. In particular, their sensi- tivity to acetone and hydrogen sulphide was the highest reported in literature. “New types of heterogeneous nanocatalysts were synthesised using protein templates with sizes around 2 nm and function- alised on various metal oxide na- nofiber sensing layers. The estab- lished sensing libraries can de- tect biomarker species with high sensitivity and selectivity. The new and innovative breath gas analysis platform will be very helpful for reducing medical ex- penditures and continuous mon- itoring of physical conditions,” said Kim. The study, titled “Innovative nanosensor for disease diagnosis”, was published in the July issue of the Accounts of Chemical Research journal. sion for sextant scanning, and 3Shape’s TRIOS the best balance of speed and accuracy for complete- arch scanning. The study, titled “Evaluation of the accuracy of 7 digital scanners: An in vitro analysis based on 3- dimensional comparisons,” was published in the July issue of the Journal of Prosthetic Dentistry. Light-curing micro-hybrid composite (cid:149) Applicable for various indications and all cavity classes (cid:149) High translucency and a perfect colour adaption (cid:149) Polishable to a high gloss (cid:149) Excellent physical properties for durable fillings (cid:149) High filler content (cid:149) Packable consistency (also available as Composan LCM flow) Visit www.promedica.de to see all our products Dental Material GmbH 24537 Neumünster / Germany +49 43 21 / 5 41 73 Tel. +49 43 21 / 5 19 08 Fax eMail info@promedica.de Internet www.promedica.de