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Dental TribuneAsia Pacific Edition | 1+2/2016 10 WORLD NEWS By DTI ANNARBOR,Mich.,USA:Anewtech- nology developed by researchers attheUniversityofMichigancould help dentists improve treatment of patients with bone loss. The sci- entists have developed a polymer sphere that delivers a specific moleculetobonewoundsthattells cells already at the injury site to repair the damage. Therefore, the nanotechnology could improve implanttreatmentorhelppatients with periodontal disease. MicroRNA, a small noncoding RNA molecule found in plants, animals and some viruses, has shown promise in clinical research as a therapeutic agent for various diseases, such as cancer and in- flammatory diseases. It might also be able to enhance bone regenera- tion, the current study has found. When delivered into endoge- nous stem cells, the microRNA in- structs the cells to switch on their healing and bone-building mech- anisms, explained Dr. Peter Ma, Professor of Dentistry and lead researcher on the project. It is typ- ically very difficult for microRNA to breach the cell wall, Ma said. However, the polymer sphere de- veloped by Ma and his colleagues enables the RNA molecule to easily enter the cell and encourage bone repair. The advantage of this new tech- nology is that it uses existing cells to repair wounds and therefore reduces the need to introduce for- eign cells, which is a very difficult therapy and can result in the host rejecting the foreign cells or the development of tumors. Bone repair is especially chal- lenging in patients with healing problems. Millions of patients worldwide suffer from bone loss and associated functional prob- lems, but growing and regenerat- ing high-quality bone for specific applications is still very difficult withcurrenttechnology,according to the researchers. “The new technology we have been working on opens doors for new therapies using DNA and RNA in regenerative medicine and boosts the possibility of dealing with other challenging human diseases,” Ma explained. There are severalpossibleapplicationsinden- tistry and maxillofacial surgery. Moreover, it could help patients with osteoporosis, as well as those undergoing bone surgery or joint repair. “For patients with low bone quality, it’s often hard to utilize im- plants to restore dental functions. This technology can potentially regenerate bone in patients with poor healing capacity, enabling implantation,” Ma told Dental Tribune. He added that patients with periodontitis could also bene- fit from his findings. “Periodontal disease often ultimately results in tooth loss due to diminishing tooth-supporting bone. This tech- nology will potentially lead to a therapy to restore the tooth- supporting bone and retain or strengthen otherwise falling teeth in such patients,”he stated. The paper, titled “Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects,” was published online in the Nature CommunicationsjournalonJan.14. New nanotechnology might improve bone restoration in dental patients 38th Asia Pacific Dental Congress Advancing Dentistry with Modern Science and Technology www.apdc2016.org On behalf of the Asia Pacific Dental Federation and the Hong Kong Dental Association, we would like to invite you to attend the 38th Asia Pacific Dental Congress (APDC 2016) to be held at Hong Kong Convention and Exhibition Centre from 17-19 June 2016. Theme ‘Advancing Dentistry with Modern Science and Technology’, APDC 2016 will be an excellent platform to meet and dissect challenges in the field with leading experts from around the world. INVITED SPEAKERS · Dr Chris Chang · Professor Monty Duggal · Dr Stanley Malamed · Professor Hsu Ming-Lun · Dr Hiroshi Ogawa · Professor Mariano Sanz · Dr Frankie So · Professor Adrian Yap · And many more… KEYNOTE & PLENARY LECTURE TOPICS · Innovations in Dental Traumatology. Tradition Versus a Bright New Future · Is the Mandibular Block Passé? · Emergency Medicine - Sudden Cardiac Arrest and AEDs? · Prevention of Peri Implant Disease for Implant Success · The Implications of Population Aging to General Dental Practice · Guided Surgery: Application in Complex Edentulous Cases and Use of a New Digital Workflow for Partial and Single Cases · Simplified Mechanics for Challenging Cases, Part I & II · Improve Population Oral Health by Targeting NCDCommon Risk Factors · “Oh My Aching Jaw”: Detection and Management of TMD in Primary Care · Bone Biomechanics of Implant Dentistry ABSTRACT SUBMISSION APDC 2016 is now accepting abstracts. Submit your abstract now and let your voice be heard! Visit www.apdc2016.org for more information. ABSTRACT TOPICS INCLUDE · Endodontics · Geriatric Dentistry · Implantology · Infection Control · Neuroscience / TMD · And many more… IMPORTANT DATES Abstract Submission Deadline: 29 February 2016 Early Bird Registration Deadline: 1 April 2016 APDC 2016 SECRETARIAT Registration & Accommodation: for your queries and requirements about registration and accommodation; -RSá0ÞNARáaOBANOÛLUá2EGISTRATIONáANDá!CCOMMODATIONá Manager E-mail: pcobanoglu@kenes.com Scientific Information: for your queries about scientific programme; Ms. Selen Akün, Scientific Programme Coordinator E-mail: sakun@kenes.com Sponsorship & Exhibition Requirements: for your queries about sponsorship & exhibition opportunities and application process; Mr. Veysel Güzel, Project Manager E-mail: vguzel@kenes.com General Details for all other queries; Mr. Veysel Güzel, Project Manager E-mail: mailto:vguzel@kenes.com -Sá-ARALá"ALIMOÛLUá0ROJECTá-ANAGER E-Mail: mbalimoglu@kenes.com 17-19 June, 2016 Hong Kong Convention and Exhibition Centre AD DTAP0116_10_Nano 12.02.16 12:59 Seite 1 DTAP0116_10_Nano 12.02.1612:59 Seite 1