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Dental Tribune United Kingdom Edition No. 1+2, 2016

Dental Tribune United Kingdom Edition | 1+2/2016 04 UK NEWS By DTI DUNDEE, UK: The Cochrane Oral Health Group in Manchester has re- centlyupdatedoneofitsreviews,find- inganykindofpreformedcrowntobe superiortofillingsinthetreatmentof severelydecayedprimarymolarsand primarymolarsthathaveundergone pulp treatment. The results also sug- gestthatoutofallfittingmethods,the Hall technique causes the least dis- comfortandproblemsforpatients. Namedafteritsinventor,aScottish dentist,theHalltechniqueusesapre- formedmetalcrownthatisfittedover the tooth with no local anaesthetic, carious tissue removal or tooth pre- paration. First introduced a decade ago, it was originally developed as a non-invasive treatment for decayed primarymolars. For their review, the researchers looked at the clinical outcomes of several studies comparing fillings with crowns that were fitted with either conventional methods or the Hall technique. They also included studies that compared preformed crowns with non-restorative caries management, as well as preformed metal crowns with preformed white crowns. Whilethereviewfoundnoevidence of the superiority of one crown type to another, the results showed that teeth restored with preformed crownscomparedwithfillingsareless likely to develop problems or cause painovertime. “Crowns are recommended for restoring primary molars that have had a pulp treatment, are very de- cayed or are badly broken down. However, few dental practitioners use them in clinical practice,” the researcherssaidinthereport. With the review, the researchers originally sought to determine whether the clinical outcome of pri- mary teeth restored with preformed crownsorwithfillingswasinanyway relatedtotheextentoftheirdecay. The review updates a previous version on the subject, originally publishedbythegroupin2007. Cochrane finds crowns superiortodentalfillings By DTI BRISTOL, UK: Scientists at the Univer- sity of the West of England (UWE) in Bristol have discovered a new way to improve the bond between titaniumimplantsandbone. They found that a bioactive lipidcalledlysophosphatidic acid (LPA) interacts with vitamin D to enhance bone- forming cell function. Based on this finding, the re- searchers have developed an LPA coating for titanium implants to help strengthen the bonding properties of implantstobone. “Many implants used in surgery are made out of titanium.Theseincludejoint replacements, screws and plates for fixing broken bones and dental implants,” said Dr Jason Mansell, a sen- ior lecturer in Biomedical SciencesatUWEBristol,who ledthestudy. “Implants work well when the pa- tient’s own bone joins onto the tita- nium using the body’s own natural healing processes. When this join formsproperlyitisextremelystrong, however in some cases, the patient’s bone fails to join strongly to the tita- nium and therefore the prosthesis works loose and ultimately fails,” Mansellexplained. Although the success rates of dental implants are high, ranging between 88 and 99 per cent in the lit- erature, several factors, such as bone quality and quantity, as well as infec- tion, can cause dental implants to fail, making reimplantation necessary.ThenewLPAcoating, developed by the researchers could further improve the suc- cessrateofdentalimplanttreat- ments. LPA is a naturally occurring fattymoleculethatactswithvi- taminDtopromotebone-form- ingcellfunction,theresearchers discovered.“This is a very excit- ing discovery as few agents are known to enhance the actions of vitamin D on bone forming cells.VitaminDisvitalforbone healthbecauseitenhancesbone forming cell function. There- fore, agents that can co-operate withvitaminDcouldfindplace as a coating on titanium to en- courage better bonding to the patient’sbone,”Mansellsaid. Basedonthisknowledge,thescien- tistsdevelopedanLPAcoatingfortita- niumimplants.“Wehavefoundaway of joining LPA onto titanium using a simple process at room temperature. Recently we also discovered that our novelcoatingalsodeterredtheattach- ment of bacteria, this is particularly exciting as it means we have a poten- tialdual-actiontitaniumimplantma- terial,”Mansellstated. Thenextstageoftheproject,which is currently seeking further funding, will examine the robustness and sta- bility of the coating, as it would need to withstand the rigors of storage, sterilisationandthephysicalforcesit wouldbeexposedtowhenimplanted intothebody. The study, titled “Fluorophospho- nate-functionalised titanium via a pre-adsorbedalkanephosphonicacid: A novel dual action surface finish for bone regenerative applications”, was publishedonlineaheadofprintinthe JournalofMaterialsScience:Materials inMedicineon24December2015. New discovery helps strengthen bonding of titanium implants to bone By DTI MANCHESTER, UK: New diagnostic technologydevelopedbyaUniversity of Manchester spin-out that could help detect early-stage enamel caries fastercouldsoonbereadytoenterthe market, as the developer has recently announced that it has received fund- ingfromaNorthernEnglandinvestor. In a commitment to expand to the North of England, Mercia Fund Man- agement has said it will invest over a quarter of a million pounds in the new software, which is claimed to be capable of spotting early caries and otherpotentialproblemsbeforethey developintosomethingmoreserious. A brainchild of University of Man- chester spin-out Manchester Imag- ing, the software uses technologies like active shape models and active appearance models, which are al- ready used in medicine and face recognition, for example, to analyse dental radiographs in order to find earlysignsofcaries. According to Manchester Imaging CEO Tony Travers, it is the first time that this kind of modelling has been appliedtodentistry. Traditionalmethodsofearlycaries detection include the use of laser- induced fluorescence or detection gels, which may however be unreli- able. “Manchester Imaging’s computer- aided dental diagnostic software has been developed to overcome the problems of early-stage identifica- tion through the use of pioneering technology that pinpoints the first traces of decay at the touch of a button,” Travers told Dental Tribune. “Itintegratesseamlesslywithexisting digitalX-rayandpracticesoftware.” According to Travers, the technol- ogy could be market ready as early as 2017. Another funding round for investorsisanticipatedforthisyear. In addition to caries detection, Manchester Imaging is working on other imaging technologies for use indentalimplantology,forexample. Funding brings Manchester diagnostic tech closer to market launch Photo showing a preformed metal crown fitted with the Hall technique. A team of researchers, led by Dr Jason Mansell from UWE Bristol, has discovered a new way to coat titanium implants in order to improve their bond to bone. DTUK0116_04_News 25.02.16 14:57 Seite 1 DTUK0116_04_News 25.02.1614:57 Seite 1

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