case report | 1b 1c Fig. 1b: Initial CT sagittal section. Fig. 1c: Initial CT cross section. follicle has 3–4 mm of space between the tooth and its margin, this cyst can be suspected when this space is larger than 5 mm.1, 8 When located in the mandible, this cyst can cause the displacement of the mandibular ca- nal, the resorption of the wall of this canal, the root re- sorption of adjacent teeth or even pathological mandib- ular fracture.9, 10 Treatment options Marsupialisation and enucleation are the classic tech- niques for the treatment of dentigerous cyst and may be associated.7, 8 Decompression, using a decompression device, is an option, when followed by enucleation, for the treatment of large cysts. However, the criteria for choosing one of these modalities are not clearly defined, owing to the lack of exhaustive studies and adequate follow-ups.11 As accepted criteria for diagnosis and treatment, the size of the cyst, the age of the patient, the teeth involved and the involvement of anatomical structures must be taken into account.1 The treatment modality to be chosen will depend on the clinical and radiographic characteristics in question. Lesion aspiration should be performed in all cases, as radiographically similar lesions can be odonto- genic tumours or vascular lesions and not cysts as ex- pected, the detection of fluid inside the lesion being a major indication of cyst.12–14 Incisional biopsy must then necessarily be performed to differentiate the type of cyst, as other lesions, such as odontogenic keratocysts and unicystic ameloblastoma, may have similar clinical and radiographic characteris- tics; however, they are more aggressive locally, requiring more extensive treatment and thus sacrifice of neurovas- cular tissue, bone and adjacent teeth.11, 12, 15 The progno- sis of dentigerous cyst is favourable and has a low recur- rence rate (3.7 %); even so, the follow-up must be strict.10 Enucleation of the cyst and extraction of the associated unerupted tooth are performed in about 85 % of cases and are the treatment of choice for small lesions with a safe distance from anatomical structures, such as the in- ferior alveolar nerve.1, 12 In these patients, this is indicated if the unerupted tooth is considered useless for masti- catory or aesthetic function or there is a lack of clinical space for its eruption.10, 11, 14 In dentigerous cysts of third mandibular molars, the larger the cyst, the greater the risk of nerve injury and weakening of the mandibular an- gle caused by the surgery. Therefore, in these cases, the most appropriate therapeutic modality would be decom- pression followed by enucleation, after reducing the size of the lesion.16–18 Bone reconstruction The two-stage treatment is time-consuming, uncomfort- able for patients and requires frequent check-ups. One- stage cystectomy of large cysts with watertight closure of the postoperative bone cavity predisposes to compli- cations. Moreover, the weakened bone structure is prone to fractures in the postoperative period. This is why there is particular interest in filling the bone cavities with auto- grafts or bone substitutes. Clinical case A 43-year-old Caucasian female patient attended the oral and maxillofacial surgery consultation at Clitrofa medical centre in Trofa in Portugal to assess extraction of teeth #38 and 48. She was asymptomatic, without paraes- thesia, hypoaesthesia or other complaints. Anamnesis established that there were no allergies or use of med- ication. On extra-oral clinical examination, no abnormal- ity was observed. On intra-oral physical examination, a slight bulging of the cortical bone was noted in the region of the left external oblique line adjacent to tooth #37, but no chromatic alteration in the oral mucosa. The dental panoramic tomogram showed a unilocular, well- defined, homogeneous radiotransparent area surrounding the dental crown of the included tooth #38, extending to the tooth #35 region (Fig. 1a). In the coronal, sagittal and 4 2020 17