C4 t Page C3 IMPLANT TRIBUNE Dental Tribune Middle East & Africa Edition | 1/2020 Discussion Autologous bone graft is character- ized by its osteoinductive, osteo- genic and osteoconductive charac- teristics rending it the treatment of choice for atrophic ridges9,10, yet it is still difficult to demonstrate which procedure is superior to the other6. Few years back the introduction of PRF technology in oral surgery made a big impact to our daily practice7. The platelet-rich plasma (PRP) which is the precursor of the platelet –rich fibrin (PRF), is a solid fibrin based biomaterial used lately in bone graft techniques. Choukroun’s PRF that includes Leucocyte and plate- let- rich fibrin (L-PRF) started being widely applied in oral surgery since it showed important results4 . In the following article, the 3 clinical cases where the bone loss was in ad- vanced levels, the use of L-PRF asso- ciated xenograft resulted in gaining time for implants placement with bone structure very similar to auto- graft in resultant bone volume. As per Tatullo and al, with the aid of PRF the healing time is significantly reduced and the implant can be placed at 4 months after surgery8. On the other hand Choukroun and al, concluded that the fibrin mol- ecule having as low polymerization mode will help enhance the healing process for the PRF membrane ob- tained 5 . The PRF associated bovine bone pro- cedure to increase the bone volume in atrophic ridges with advanced defects is clinically worthwhile be- cause of its simplicity and the good treatment results8. As it shows the follow-up period is acceptable and the preliminary results did not show any failures. As per our 3 clinical cases, bone maturation was found excellent at 5 months as seen clinically and on X-rays and CAT scans making it a re- liable treatment in cases of atrophic ridges. Conclusion The continually evolving field of PRF strives to create results similar to those with autologous bone graft. AD The 3 clinical cases reported in the present article achieved a clinical and radiological success by using the PRF associated bovine bone protocol. The use of xenograft combined with L-PRF allowed fast soft and hard tis- sue healing with less traumatic pro- cedure for patients with reconstruc- tion of alveolar ridges at the gingival and bone level very similar to au- togenous bone graft techniques. Pa- tients were overwhelmed with the aesthetic results obtained in a very limited time margin. In the light of the following technique, the results were faster compared to autologous bone graft procedure. We are invited today to accept the transition in us- ing PRF in oral surgery due to its satisfactory results achieved using a minimal invasive procedure. Surg.2009;67: References 1. Contar CM, Sarot JR, Bordini J Jr, et al. Maxillary ridge augmentation with fresh-frozen bone allografts. J Oral Maxillofac Surg 2009;67: 1280- 1285. 2. Barone A, Varanini P, Orlando B, et al. Deep-frozen allogeneic onlay bone grafts for reconstruction of atrophic maxillary alveolar ridges: A preliminary study. J Oral Maxil- lofac 1300-13063 3. Lauritano D, Avantaggiato A. Is platelet-rich fibrin really useful in oral and maxillofacial surgery? Lights and shadows of this new tech- nique. Annals of Oral and Maxillofa- cial surgery2013;1(3):25. 4. Cieslik-Bielecka A., Dohan Ehren- fest DM. Microbicidal properties of leukocyte-and platelet-rich plasma/ fibrin(L-PRP/L-PRF): new perspec- tives. J Biol Regul Homeost Agents. 2012; 26(2 Suppl 1):43-52. 5. Dohan D, Choukroun J, Diss A. Platelet-rich fibrin (PRF): A second- generation platelet concentrate. Part I: Technological concepts and evolu- tion. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 101:37-44. 6. Chiapasco M, Casentini P. Bone augmentation procedures in im- plant dentistry. Int J Oral Maxillofac Implants 2009: 237-259. 7. Anitua E, Sanchez M. New insights into and novel applications for plate- let-rich fibrin therapies. Trends in biotechnology 2006; 24(5): 227-234. 8. Tatullo M, Marrelli M. Platelet Rich Fibrin (P.R.F) in reconstructive sur- gery of atrophied maxillary bones: Clinical and histological evaluations. Int J Med Sci 2012; 9(10):872-880 9. Preti G. Implantologia: Nuove ac- quisizionie aspetti clinici: int: Riabili- tazione Prostesica.UTET:2003:203- 206. 10. Lekholm U, Wannfors K. Oral Implants in combination with bone grafts. Int J Oral Maxillofac Surg 1999; 28: 181-187. About the authors Carine Tabarani, DDS, MSC ORAL SURG, IMP, ORAL MED Specialist Oral surgery and implantol- ogy, Oral medicine. Senior lecturer, department of topo- graphic anatomy Saint Joseph Univer- sity, Beirut, Lebanon. French Dental and Aesthetic center Abu Dhabi-UAE Musa Jaffal Specialist Orthodontist French Dental and Aesthetic Center Abu Dhabi, UAE. Rabih Abi Nader, DDS, MSC ORAL SURG, ORAL MED. Specialist Oral surgery and implantol- ogy, Dubai sky clinic-Dubai- UAE