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I n d i v i d u a l i z e d t i t a n i u m s c a f f o l d s Individualized CAD/CAM-produced titanium scaffolds for alveolar bone augmentation: A retrospective analysis of dehiscence events in relation to demographic and surgical parameters Marcus Seiler,a Michael Peetz,a Amely Hartmanna & Radoslaw Witkowskia a Clinic of Oral and Maxillofacial Surgery, Center for Oral Implantology, Filderstadt, Germany C o r r e s p o n d i n g a u t h o r : Dr. Marcus Seiler Clinic of Oral and Maxillofacial Surgery Center for Oral Implantology Echterdinger Str. 7 70794 Filderstadt Germany T +49 711 700 9470 seiler@implantologie-stuttgart.de H o w t o c i t e t h i s a r t i c l e : Seiler M, Peetz M, Hartmann A, Witkowski R. Individualized CAD/CAM-produced titanium scaffolds for alveolar bone augmentation: A retrospective analysis of dehiscence events in relation to demographic and surgical parameters. J Oral Science Rehabilitation. 2018 Mar;4(1):38–46. Abstract O b j e c t i v e s Computer-aided design/computer-aided manufacturing (CAD/CAM) technologies may improve application of titanium scaffolds, onlay tech- niques and guided bone regeneration. In this study, the clinical outcome of DICOM-based individualized CAD/CAM-produced titanium scaffolds (iCTSs) was analyzed in grafted defects, particularly with regard to rela- tion of dehiscence to demographic and surgery-related factors. M a t e r i a l s a n d m e t h o d s In 100 patients, 115 defects of the alveolar crest were reconstructed with an iCTS covered with a native bilayer collagen membrane or left uncov- ered. The volume was mostly grafted with a mixture of autogenous bone and deproteinized bovine bone mineral. The healing process was docu- mented. Office records were analyzed for association of dehiscence with demographic and surgical parameters. R e s u l t s Uneventful healing was observed in 82 defects. Infection of the surgical area was documented in 11 cases, 10 were resolved by medication. One defect had to be regrafted. Dehiscence was reported in 26 defects. Pre- mature removal of exposed iCTSs was not necessary. All of the cases showed sufficiently grafted volume for implant placement with presur- gical 3-D planning. The grafted volume in the defects with dehiscence did not differ from that in sites without dehiscence. Statistical analysis revealed no significant association of dehiscence with demographic or surgical parameters, but a tendency to higher prevalence of dehiscence with mesiodistal width of the defect. C o n c l u s i o n Combination of an iCTS with guided bone regeneration offers a reliable grafting technique with low sensitivity to dehiscence. Dehiscence did not correlate with demographic or surgical factors. In addition, it did not affect the final outcome, as implant insertion was possible simultane- ously or staged in all of the cases. K e y w o r d s CAD/CAM, individual titanium scaffold, augmentation, wound dehiscence. 38 Volume 4 | Issue 1/2018 Journal of Oral Science & Rehabilitation