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Journal of Oral Science & Rehabilitation No. 1, 2018

S i n u s l i f t a n d M g-e H A/co l l a g e n-b a s e d s c a f f o l d Fig. 3 Digital panoramic radiograph 12 months after prosthetic loading. Fig. 3 panoramic radiographs, with the ability to com- pensate for eventual radiographic distortion.14, 15 All measurements were conducted and recorded by the same trained independent examiner, with- out input from the implant surgeon. S t a t i s t i c a l a n a l y s i s Descriptive statistics, including mean values and standard deviation, were used to describe changes in implant stability over the time and bone area. Student’s t-test for paired data was performed to test the significant difference between ISQ values at T0, T1 and T2. Student’s t-test was used to perform bone area compari- son. Significance was set at P > 0.05. Results A total of 13 consecutive patients (8 females and 5 males) were treated. The mean age was 62.1 years (SD: 11.05 years). No patient dropped out during the study. The preoperative mean residual bone level was 2.5 mm (SD: 1.0 mm). Minimal perforation of the sinus membrane occurred in 4 cases. The healing period after sinus augmentation was without complication for all of the patients. Minor nosebleeds occurred in 1 case. No clinical symptoms of max- illary sinusitis occurred in any patient. Only 1 implant was mobilized during the uncovering procedure, in a light smoker. For the failed implant, the preoperative height was 2 mm, the ISQ value was 39 at T0 and 42 at T1. The patient did not report any symptoms during the healing period. After surgical debridement, the implant was substituted with an implant 6 mm in diam- eter at the same surgical stage and restored after an additional 3 months of healing. All of the other implants were osseointegrated after 12 months of prosthetic loading (cumulative survival rate: 96.15%). The mean ISQ value was 42.5 (SD: 2.7) at T0, 75.3 (SD: 8.2) at T1 and 81.5 (SD: 2.6) at T2. Sta- tistically significant differences (P ≤ 0.0005) regarding mean ISQ values were found between T1 and T0, as well as between T1 and T2. The mean radiographic vertical height of the grafted sinus floor was 13.75 mm (SD: 1.30 mm) after 12 months of prosthetic loading (P ≤ 0.0005). Discussion This prospective study demonstrated that, even in critical conditions, osseointegration and longi- tudinal stability of implants with a rough surface over their entire length could be a reliable clinical outcome when placed in maxillary sinuses grafted with a biomimetic Mg-e HA. Additionally, the use of an Mg-e HA/collagen-based scaffold with a porous 3-D structure seems to prevent surgical complications due to microperforation of the Schneiderian membrane. The main limitations of the present study were the short-term follow-up (1 year) and small sample size (13 patients). However, this study is a preliminary report proving the feasibility of the combination of an Mg-e HA/collagen-based scaffold with a biomimetic HA. Additionally, the absence of a control group does not allow for demonstration of any additional benefit com- pared with the gold standard in sinus lift surgery. 12 Volume 4 | Issue 1/2018 Journal of Oral Science & Rehabilitation

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