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1 - y e a r s t u d y o f n o n s u b m e r g e d i m p l a n t s Multifactorial statistical analysis toward evaluation of MBL, PES and PI of a novel non- submerged implant to restore a single tooth: A 1-year prospective cohort study Carlo Prati,a Fausto Zamparini,a, b Chiara Pirani,a Lucio Montebugnolia & Maria Giovanna Gandolfib a Endodontic Clinical Section, Department of Biomedical and Neuromotor Sciences, School of Dentistry, University of Bologna, Bologna, Italy b Laboratory of Biomaterials and Oral Pathology, Depart- ment of Biomedical and Neuromotor Sciences, School of Dentistry, University of Bologna, Bologna, Italy C o r r e s p o n d i n g a u t h o r : Prof. Carlo Prati Via San Vitale, 59 40125 Bologna Italy T +39 051 208 8126 carlo.prati@unibo.it H o w t o c i t e t h i s a r t i c l e : Prati C, Zamparini F, Pirani C, Montebugnoli L, Gandolfi MG. Multifactorial statistical analysis toward evaluation of MBL, PES and PI of a novel nonsubmerged implant to restore a single tooth: A 1-year prospective cohort study. J Oral Science Rehabilitation. 2017 Dec;3(4):32–41. Abstract O b j e c t i v e The objective of this study was to evaluate radiographic, clinical and esthetic parameters of a new type of nonsubmerged 2-piece implant placed in patients in need of single-tooth replacement. M a t e r i a l s a n d m e t h o d s Fifty-four consecutive patients requiring single-tooth replacement received 62 2-piece nonsubmerged flapless implants characterized by an innovative hyperbolic neck. The implant placement timing was as follows: 15 immediately post-extraction (immediate), 18 after 8–12 weeks (early) and 29 after 10–12 months (delayed). Customized abut- ments with an abutment–implant connection approximately 1–2 mm above the soft-tissue level were positioned after 3 months, loaded with provisional crowns and 20 days later with definitive crowns. Gingival biotype (thin or thick) was investigated in all patients. Peri- implant marginal bone level (MBL; mm) was measured single-blinded on periapical radiographs at 1, 3, 6 and 12 months (T1, T3, T6, T12). Papilla index (PI), plaque score and bleeding on probing (BoP) were evaluated as clinical parameters of soft tissue. Pink Esthetic Score (PES) was calculated as the esthetic parameter. R e s u l t s The survival rate was 100%. The dropout rate was 1.85%. The mean MBL was - 0.01 ± 0.26 at T1, - 0.17 ± 0.38 at T3, - 0.28 ± 0.32 at T6 and - 0.37 ± 0.41 at T12. The PES (0–14) was 7.30 ± 2.80 at T0 (preoperatively), 11.06 ± 0.97 at T6 and 11.95 ± 1.04 at T12. At (T12), delayed implants showed a greater (P < 0.05) bone loss compared with early and immediate implants. Implants placed in thin biotype tissue showed the greatest bone loss at 12 months with a significant (P < 0.01) difference with respect to that at (T6). PES and PI increased from T0 to T12. C o n c l u s i o n These implants allow preservation of a good MBL and offer a new approach to soft- and hard-tissue management, allowing a reduced healing time with minimally invasive surgery, no additional re-entry and fewer complications. K e y w o r d s Nonsubmerged dental implants, flapless surgery, marginal bone level (MBL), papilla index (PI), bleeding on probing (BoP), Pink Esthetic Score (PES). 32 Volume 3 | Issue 4/2017 Journal of Oral Science & Rehabilitation