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ePaper created 2017-10-20, 09:29:03 | version 1.38.0
22 趋势与应用 图1：Geistlich Bio-Gide®早期血管化，提供了贯穿植骨区 图2：不可通透膜将新血管的形成局限于植骨边缘区域。 图3：Geistlich Bio-Gide®膜的早期血管化是骨再生的关键步骤。 域的血供。 2周 6周 12周 Geistlich Bio-Gide® Geistlich Bio-Osse® Collagen newly formed bone 功。拥有独特的高度生物相容性，快速 创口稳定性，营养物质吸收和组织整合 特性的Geistlich Bio-Gide®膜也提供了软 组织美学修复的功能——Geistlich Bio- Gide®不仅仅是一层屏障膜。 参考文献 > Becker J, et al.: Use of a new cross- linked collagen membrane for the treatment of dehiscence-type defects at titanium im- plants: a prospective,randomized-controlled double-blinded clinical multicenter study. Clin Oral Implants Res 2009; 20(7): 742-9. > Hurley LA, et al.: The role of soft tissues in osteogenesis: an experimental study of canine spine fusions. J Bone Joint Surg Am 1959; 41:1243-66. > Kanczler JM, Oreffo ORC: Osteo- genesis and angiogenesis: the potentialfor engineering bone. Eur Cells and Materials 2008; 15: 100-14. > S chmid J, et al.: The significance of angiogenesis in guided bone regeneration. A case report of a rabbit experiment. Clin Oral Implants Res 1997; 8(3): 244-8. > S chwarz F, et al.: Angiogenesis pattern of native and cross-linked collagen membranes: an immunohistochemical study in the rat. Clin Oral Implants Res 2006; 17(4): 403-9. > S chwarz F, et al.: Immunohis- tochemical characterization of guided bone regeneration at a dehiscence-type defect using different barrier membranes: an experimental study in dogs. Clin Oral Implants Res 2008; 19(4): 402-15. > S hapiro F: Cells and Materials. 2008; 15: 53-76. Relevant excerpt original- ly from Pauwels 1976, [English translation] and Weinans and Prendergast, 1996. > Tal H, et al.: Long-term bio-degra- dation of cross-linked and noncross- linked collagen barriers in human guided bone regeneration. Clin Oral Implants Res 2008; 19(3): 295-302. > Wang Y, et al.: Oxygen Sensing and Osteogenesis. Ann N Y Acad Sci 2007; 1117: 1-11. 早期血管化的优势在于： 1 有利于成骨 2 有助伤口愈合 3 有利于氧份和营养物质转移 4 组织融合 5 伤口愈合无并发症 www.dentistx.com