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implants_terapie wspomagające działań smaku i zapachu, jest łatwy w aplikacji, nie wykazuje niepożądanych i interakcji z innymi lekami. Jest stosunkowo tanią i ogólnodostępną substancją. Może być bezpiecznie stosowany jako substancja wspomagająca terapię. Piśmiennictwo: 1. 2. 3. 4. 5. 6. 7. 8. 9. Olczyk P, Komosińska-Vassev K, Winsz-Szczotka K, Kuźnik-Trocha K, Olczyk K. Hialuronian – struktura, metabolizm, funkcje i rola w procesach gojenia ran. Postepy Hig Med Dosw. (online), 2008; 62: 651-659. Chen WY, Abatangelo G. Functions of hyaluronan in wound repair. Wound Repair Regen., 1999; 7: 79-89. David-Raoudi M, Tranchepain F, Deschrevel B, Vincent JC, Bogdanowicz P, Boumediene K, Pujol JP. Differential effects of hyaluronan and its fragments on fi broblasts: relation to wound healing. Wound Repair Regen., 2008; 16: 274-287. Casale M, Moffa A, Vella P, Sabatino L, Capuano F, Salvinelli B, Lopez MA, Carinci F, Salvinelli F. Hyaluronic acid: Perspectives in dentistry. 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A roentgenographic assessment of regenerative efficacy of bioactive Gengigel(®) in conjunction with amnion membrane in grade II furcation defect. Contemp Clin Dent. 2015 Apr-Jun;6(2):277-80. 14. Gontiya G, Sushama R, Galgali SR. Effect of hyaluronan on periodontitis: A clinical and histological study. J Indian Soc Periodontol. 2012 Apr-Jun; 16(2): 184-192. 15. Gupta S, Kediege SD, Gupta A, Jain K. Evaluation of Gengigel® Application in the Management of Furcation with Coronally Advanced Flap through Surgical Re-Entry-A Split Mouth Clinical Study. J Clin Diagn Res. 2017 Jan;11(1):ZC27-ZC32. 16. Sehdev B, Bhongade ML, Ganji KK. Evaluation of effectiveness of hyaluronic acid in combina- tion with bioresorbable membrane (poly lactic acid-poly glycolic acid) for the treatment of infrabony defects in humans: A clinical and radiographic study. J Indian Soc Periodontol. 2016 Jan-Feb;20(1):50-6. 17. Rajan P, Baramappa R, Rao NM, Pavaluri AK, PI, Rahaman SM. 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Zastosowanie indywidualnej siatki tytanowej w augmentacji wyrostka zębodołowego szczęki z wykorzystaniem rhPDGF – część 1. Implants 2016 Jan 32-35. 22. Lokeshwar VB, Lopez LE, Munoz D, Chi A, Shirodkar SP, Lokeshwar SD, Escudero DO, Dhir N, Altman N. Antitumor activity of hyaluronic acid synthesis inhibitor 4-methylumbelliferone in prostate cancer cells. Cancer Res. 2010 Apr 1;70(7):2613-23. 23. Hamlet SM, Vaquette C, Shah A, Hutmacher DW, Ivanovski S. 3-Dimensional functionalized polycaprolactone-hyaluronic acid hydrogel constructs for bone tissue engineering. J Clin Periodontol. 2017 Apr;44(4):428-437.