Please activate JavaScript!
Please install Adobe Flash Player, click here for download

Implant Tribune Asia Pacific Edition

18 IMPLANT NEWS Implant Tribune Asia Pacific Edition | 4/2017 Nano-coating effective in reducing peri-implantitis risk By DTI PLYMOUTH, UK: Investigating the effect of a new approach using a combination of silver, titanium di- oxide and hydroxyapatite (HA) nano-coatings on the surface of titanium alloy implants, research- ers from Plymouth have found that the method was successful in inhibiting bacterial growth and reducing the formation of bacte- rial bioilm. In addition, the coat- ing created a surface with anti-bi- oilm properties, thus supporting successful integration of the im- AD 201720172017 Hong Kong International Dental Expo HKIDEAS And Symposium 4 – 6 AU G U ST Hong Kong Convention and Exhibition Centre www.hkideas .org C A L L F O R A B S T R A C T Deadline: 15 April 2017 E A R LY - B I R D R E G I S T R A T I O N Deadline: 15 May 2017 P R E L I M I N A R Y F A C U LT Y Professor Patrick Allen (Singapore) – Geriatric Dentistry Dr. Yu-chih Chiang (Taiwan) – Restorative Dentistry Dr. Jeanette Chua (Malaysia) – Periodontics Dr. Peter Pospiech (Germany) – Prosthodontics Professor Iain Pretty (United Kingdom) – Preventive Dentistry Dr. Alan Reid (Australia) – Medical Emergency N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y N E W H O R I Z O N I N D E N T I S T R Y Organizer plants into surrounding bone and accelerating bone healing. One of the main reasons for dental implant failure is peri-im- plantitis, an inlammatory pro- cess affecting the soft- and hard- tissue surrounding dental im- plants caused by pathogenic mi- crobes that develop into bioilms. Current approaches to managing the development of bioilms in- clude application of antimicrobial coatings loaded with antibiotics or chlorhexidine. However, these are usually only short-term meas- ures. In addition, chlorhexidine has been reported to be poten- tially toxic to human cells. Investigating a new approach, researchers from the University of Plymouth tested the effectiveness of a dual-layered silver–HA nano- coating on titanium alloy medical implants. The antibacterial per- formance of the coating was quan- titatively assessed by measuring the growth of Streptococcus san- guinis, the proportion of live and dead cells, and lactate production by the microbes over 24 hours. The results showed that the combination successfully inhib- ited bacterial growth and reduced the formation of bacterial bioilm on the surface of the implants by 97.5 per cent. Uncoated controls and titanium dioxide nano-coat- ings showed no antibacterial effect. According to the researchers, no dissolution was detected for the HA nano-coatings. Thus, appli- cation of a dual-layered silver–HA nano-coating on titanium alloy implants further created a surface with anti-bioilm properties with- out compromising the HA bio- compatibility required for suc- cessful osseointegration and ac- celerated bone healing. “In this cross-faculty study we have identiied the means to protect dental implants against the most common cause of their failure. The potential of our work for increased patient comfort and satisfaction, and reduced costs, is great and we look forward to translating our indings into clinical practice,” commented Prof. Christopher Tredwin, Head of the Peninsula School of Dentistry. In the next step, the effective- ness of the approach needs to be tested in vivo, according to the researchers. The study, titled “Antibacterial activity and bioilm inhibition by surface modiied titanium alloy medical implants following appli- cation of silver, titanium dioxide and hydroxyapatite nanocoatings”, was published online on 17 March in the Nanotoxicology Journal.

Pages Overview