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I m p l a n t a n d o r t h o d o n t i c t r e a t m e n t Comprehensive rehabilitation and natural esthetics with implant and orthodontics (CRANIO): An interdisciplinary approach to missing maxillary lateral incisors Marco Tallarico,a Cesare Luzi,b Giorgia Galasso,c Roberta Lioned & Paola Cozzad a Private practice, Rome, Italy; Surgical, Micro-Surgical and Medical Science Department, University of Sassari, Sassari, Italy; and Osstem AIC, Italy b Private practice, Rome, Italy; and Department of Orthodontics, University of Ferrara, Ferrara, Italy c Orthodontics Postgraduate Training Program, Depart- ment of Pediatric Surgery, Bambino Gesù children’s hospital, Rome, Italy d Department of Clinical Sciences and Translational Medicine, University of Rome “Tor Vergata,” Rome, Italy; and Department of Dentistry, “Nostra Signora del Buon Consiglio” University, Tirana, Albania C o r r e s p o n d i n g a u t h o r : Dr. Marco Tallarico Via di Val Tellina 116 00151 Rome Italy T +39 328 075 8769 me@studiomarcotallarico.it H o w t o c i t e t h i s a r t i c l e : Tallarico M, Luzi C, Galasso G, Lione R, Cozza P. Comprehensive rehabilitation and natural esthetics with implant and orthodontics (CRANIO): an interdisciplinary approach to missing maxillary lateral incisors. J Oral Science Rehabilitation. 2017 Mar;3(1):8–16. Abstract B a c k g r o u n d The absence of the maxillary lateral incisors creates a functional and esthe- tic problem that can be managed with diferent treatment modalities. C a s e p r e s e n t a t i o n The present case is reported to illustrate an interdisciplinary approach involving orthodontics and restorative dentistry to manage the case of a 24-year-old Caucasian female with agenesis of the maxillary right lateral incisor, presence of the maxillary right canine in place of the lateral incisor, microdontia of the maxillary left lateral incisor, and midline deviation. Treatment included space opening and positioning of a 3 mm implant supporting a single-unit crown, placed using computer-assisted, template- guided surgery. C o n c l u s i o n Comprehensive interdisciplinary rehabilitation according to the CRANIO philosophy was efective in successfully restoring function and esthetics in a young female patient afected by congenitally missing maxillary lateral incisor. K e y w o r d s Interdisciplinary treatment, agenesis, dental esthetics, dental implants, guided surgery. 08 Volume 3 | Issue 1/2017 Journal of Oral Science & Rehabilitation