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22 Revisione della Letteratura Implant Tribune Italian Edition - Marzo 2017 < pagina 21 Furthermore, in a series of stud- ies by Merli et al., the inter-rater agreement in the diagnosis of periimplant disease was judged as merely good, owing to the un- clear definition of periimplanti- tis and mucositis, with complete agreement obtained only in half of the cases (52%).80 The vast majority (45%) of the studies included in the present review found radiographic MBL > 1–2 mm after prosthetic loading. Hence, the following criteria for defining periimplantitis are pro- posed: a radiographic MBL > 1 mm after implant prosthesis delivery or 2 mm at least six months after implant prosthesis placement as a good indicator of periimplantitis. BOP does not possess a high pre- dictive value owing to the weak soft-tissue connection around dental implants. Likewise, PPD largely relies on im- plant design (bone vs. tissue level), apicocoronal position and biotype. 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