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| industry report teeth whitening and remineralisation Fig. 3 Fig. 4 Fig. 5 Fig. 3: nHAp agent by PrevDent can be used also during orthodontic treatment. Fig. 4: Initial situation. Fig. 5: Final result, after bleaching and remineralisation with nHAp by PrevDent. Studies and new product compliant with EU regulations To put professional teeth whitening therapy back into the hands of qualified dentists, new technology had to be developed to deliver great and safe results and still comply with the EU regulations. This ap- plied not only to whitening agents with just 6 % hydrogen peroxide, but also finding new additives to increase the value and results of teeth whitening treatment, and on challenging cases with hyper- sensitive teeth and gums. The regulations made it necessary to go back to studies carried out in 2010 by a Japanese University (Kawamata et al.) as well as the University of India- napolis to find a new product. All over the world, teeth whitening scientists were waiting for the discovery—or rather, rediscovery—of the additive nHAp: nanohydroxyapatite. Discovery of nHAp— nanohydroxyapatite Multiple studies had previously shown several pos- itive effects of nHAp on solid tooth structures as enamel, dentine and on gingival soft tissues leading to reduction of tooth decay and periodontitis or gum disease. The application of nHAp provides a remineralisation of the tooth surface and seals sensitive dentine tu- bules. The nHAp remineralisation is an active agent against white spots and early enamel lesions. Nano- hydroxyapatite helps to effectively remineralise the erosions on teeth caused by soft drinks, for example. With a new smoother tooth surface, bacterial adhe- sion is decreased and fewer periodontal infections occur. As result of the studies, the World Health Organi- zation (WHO) announced that nHAp could become the effective and economical prevention therapy for third world countries. Thanks to the University of Indianapolis for discovering that teeth whitening with 6 % hydrogen peroxide simultaneously with nHAp reduces all the well-known painful and nega- tive side effects of teeth whitening. Currently, their studies are leading to brilliant teeth whitening re- sults without sensitivities during and after the teeth whitening process. This is a massive breakthrough in teeth whitening over the past few decades. Results of nHAp From these results, the Dutch company PrevDent created patents for teeth whitening combined with nHAp, the first EU-legal teeth whitening product with an intensive simultaneous remineralisation. The new developments and changes by this tech- nology for the sensitive patient are visible, detect- able and remarkable. In the past, hypersensitive patients with exposed dentine structures had severe challenges with teeth whitening products. To make these conditions pos- sible to treat, patients visited the clinic several times for desensitisation therapy before the teeth whit- ening appointment. Multiple fluoridations of the tooth surface and multiple use of amorphic calcium phosphate (ACP) started weeks in advance of the treatment and were standard procedure. Before, during and after the teeth whitening pro- cedure, the patient had to consume painkillers and anti-inflammatories as a recommended therapy. Without any kind of preventive desensitisation pro- gramme, teeth whitening therapy was not possible. Now even patients with sensitive teeth and exposed dentine can have painless teeth whitening without other side effects. The combined teeth whitening therapy is called ‘In-Office Repair Whitening’ by PrevDent. How to achieve excellent results with only 6 % hydrogen peroxide PrevDent did their homework, used scientific re- search, and patented a device to arrive at the best and safest results while at the same time meeting EU regulations. The active ingredients in in-office repair whitening create an interactive reaction between 6 % hydrogen peroxide combined with a 48 cosmeticdentistry 1 2017