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Dental Tribune Middle East & Africa Edition | 1/2017 NEWS 36 New research suggests sleep bruxism might be genetically linked ByDTI TEMUCO, Chile: New research from Chile suggests that some forms of bruxism might be genetically deter- mined. Investigating genetic poly- morphisms and certain mutations in the genotype of patients with sleep bruxism, awake bruxism and patients suffering from both condi- tions, the study showed that sleep bruxism was more than twice as common among carriers of a muta- tioninaserotoninreceptorgene. Previous research suggested that neurotransmitters of the central nervous system and their genes could be involved in the genesis of bruxism. For example, medication with selective serotonin reuptake inhibitors have shown to trigger epi- sodes of bruxism in some individu- als. Aiming to shed light on this con- nection, a group of researchers from theUniversityoftheFrontier(UFRO) in Chile evaluated several serotonin- related genes in 130 patients with some form of bruxism. In the study group,61patientshaddaytimebrux- ism, 26 suffered from sleep bruxism and 43 were diagnosed with both conditions. When comparing the genetic fre- quencies of the bruxers with those of 59 healthy patients, the UFRO re- searchers found a significant differ- ence in the gene coding for the sero- tonin 5-HT2A receptor, a subtype of 5-HT2 receptors that belongs to the serotoninreceptorfamily. The findings suggest that polymor- phisms in serotonergic pathways are involved in sleep bruxism, the researchers wrote. However, as the connection to serotonin-related genes was only found in the sleep bruxism patients, while no other genetic associations could be identi- fied, further research is required to clarify and increase the current un- derstanding of bruxism physiopa- thology,theyconcluded. The study, titled “Genetic polymor- phisms in the serotonergic system are associated with circadian mani- festations of bruxism”, was pub- lished in the November issue of the JournalofOralRehabilitation. Bruxism affects one in five adults anduptoabillionpeopleworldwide. Theconditioncancauseseveredam- age to dentition and dental restora- tions. Various studies have found that bruxism is more common among individuals who have an ex- isting sleep disorder such as snoring, breathing pauses during sleep and obstructive sleep apnoea. Further- more, the condition has also been associated with mental disorders, anxietyandstress. Dentsply Sirona successfully introduces Celtra® Duo the Zirconia-Reinforced Lithium Silicate milling Block in Dubai ByDentalTribuneMEA/CAPPmea DUBAI, UAE: Dentsply Sirona suc- cessfully launched Celtra® Duo, the new Zirconia-Reinforced Lithium Silicate (ZLS) milling Block for end- users in the Middle East. On 20th of January 2017, around 25 VIP end- users were invited to the Park Hyatt Hotel Dubai Creek to find out more onthenewblockfromDr.BobConte, USA (Advanced CEREC trainer, Siro- na Beta tester and long-term CEREC user) and Dr. Markus Vollmann, Ger- many (Head of Alloys and Ceramics at Dentsply Sirona and the inventor ofCeltra®Duo). Dr Amro Adel - General Manager Dentsply Sirona officially introduc- ingtheCeltra®DueZLSinDubai. Dentsply Sirona’s new fully crystal- ized Celtra® Duo ZLS milling block contains high glass content and fea- tures a zirconia-reinforced lithium silicate microstructure. The block is invented to produce natural-looking restorations through its durability, translucency and opalescence. Cel- tra®DuoZLSistheonlymillingblock materialthatcanbeprocessedintwo different ways providing the dental professional complete control for in- dividualrestorativecases. The newly launched milling block is a threefold functional zirconia-rein- forcedlithiumsilicate(ZLS)indicated for single-unit restorations such as veneers, inlays, onlays and crowns. It can be processed in two ways – milled and fired or milled and pol- ished. This allows dental profession- alstobeincompletecontroloverthe solution they apply for individual restorative cases. The Celtra® Duo ZLS can be used with the same mill- ingunitsasall-ceramicrestorations. During the launch in Dubai, Dr. Markus Vollmann, Dentsply Sirona Head of Alloys and Ceramics in Germany introduced the technical overview on the newly launched milling block. This inspired several interesting discussions between the VIP gathering and Dr. Vollmann who quickly guided questions to the appropriate evidence whilst con- cluding the morning session. In the afternoon, Dr. Bob Conte, a private clinician from Rhode Island, USA who has over 10 years of CEREC ex- perience, showcased several clinical cases and provided hands-on dem- onstrations on case-based proper applicationincludingtipsandtricks. “Celtra® Duo was specifically de- signed to provide doctors and pa- tients with unique benefits that no other block holds,” remarked Dr. Markus Vollmann. “Optimized aes- thetics combined with a two-path- way option in one fully crystallized block enables clinicians to place a durable, naturally shaded, beautiful restoration. With an ultra-fine mi- crostructure, the blocks are milled in a final crystallized state, possess- ing outstanding polishing proper- ties and allowing the clinician the ability to shade match directly from the milling unit. We have already received remarkable feedback from both clinicians and patients on this revolutionary new restorative solu- tion.” Dental professionals in the Middle East are now able to start using Cel- tra® Duo ZLS milling block for their restorative cases. Contact your near- est Dentsply Sirona representative for more information on the new millingblock. Dr.BobConte,USA Dr. Bob Conte graduated from the University of Connecticut School of Dental Medicine in 1993 and has been in private practice in Warwick, RIforthepast23years. The busy 2 doctor practice is largely restorative-based with CEREC at the coreofeverydayactivities. •10YearsCERECexperience •SironaBetaTester • Patterson and Sirona Basic and Ad- vancedTrainer • Faculty Spear Center for Dentistry inScottsdale,Arizona SPEAKERS Dr.MarkusVollmann,Germany Dentsply Sirona Head of Alloys and Ceramics in Germany. More than 14 years experience in dental materi- als in the area of industrial Research & Development. He studied at the University of Aachen (RWTH) with a majorfocusinall-ceramic,alloysand newmaterialsandisanengineerand physicistbytraining. Over25VIPend-userswereinvited to theParkHyatt HotelDubaiCreekfor thelaunchofCeltra®Duo byDentsplySirona •FacultyCERECDoctors.com •ModeratorRI/SEMassCERECStudyClub As a CEREC Trainer, Dr. Conte has educated thousands of dentists on the CEREC process, lectured extensively on CEREC and restorative dentistry, and hasseveralarticlespublishedonthesubject. PollyRutt RegionalMarketingLeader RegionalCommercialOrganisation– EOC–MEA Mobile+971569966052(UAE) polly.rutt@dentsplysirona.com www.dentsplysirona.com