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ePaper created 2016-04-13, 11:38:23 | version 1.38.0
IMPRINT PUBLISHER: Torsten OEMUS GROUPEDITOR/MANAGINGEDITORDTAP&UK: Daniel ZIMMERMANN newsroom@dental-tribune.com CLINICALEDITOR: Magda WOJTKIEWICZ ONLINEEDITOR: Claudia DUSCHEK EDITOR: Anne FAULMANN ASSISTANTEDITOR: Kristin HÜBNER COPYEDITORS: Sabrina RAAFF, Hans MOTSCHMANN PRESIDENT/CEO: Torsten OEMUS CFO/COO: Dan WUNDERLICH MEDIASALESMANAGERS: Matthias DIESSNER Peter WITTECZEK Maria KAISER Melissa BROWN Weridiana MAGESWKI Hélène CARPENTIER Antje KAHNT INTERNATIONALPR&PROJECTMANAGER: Marc CHALUPSKY MARKETING&SALESSERVICES: Nicole ANDRAE ACCOUNTING: Karen HAMATSCHEK BUSINESSDEVELOPMENT: Claudia SALWICZEK-MAJONEK EXECUTIVEPRODUCER: Gernot MEYER ADPRODUCTION: Marius MEZGER DESIGNER: Franziska DACHSEL INTERNATIONALEDITORIALBOARD: Dr Nasser Barghi, Ceramics, USA Dr Karl Behr, Endodontics, Germany Dr George Freedman, Esthetics, Canada Dr Howard Glazer, Cariology, USA Prof.DrI.Krejci,ConservativeDentistry,Switzerland Dr Edward Lynch, Restorative, Ireland Dr Ziv Mazor, Implantology, Israel Prof. Dr Georg Meyer, Restorative, Germany Prof. Dr Rudolph Slavicek, Function, Austria Dr Marius Steigmann, Implantology, Germany PublishedbyDTI. DENTALTRIBUNEINTERNATIONAL Holbeinstr. 29, 04229, Leipzig, Germany Tel.: +49 341 48474-302 Fax: +49 341 48474-173 info@dental-tribune.com www.dental-tribune.com RegionalOffices: UNITEDKINGDOM BairdHouse,4th Floor,15–17St.CrossStreet London EC1N 8UW www.dental-tribune.co.uk info@dental-tribune.com DTASIAPACIFICLTD. c/o Yonto Risio Communications Ltd, 20A, Harvard Commercial Building, 105–111 Thomson Road, Wanchai Hong Kong Tel.: +852 3113 6177 Fax: +852 3113 6199 DENTALTRIBUNEAMERICA,LLC 116 West 23rd Street, Suite 500, New York, NY 10001, USA Tel.: +1 212 244 7181 Fax: +1 212 224 7185 ©2016,DentalTribuneInternationalGmbH All rights reserved. Dental Tribune makes every effort to report clinical information and manufac- turer’sproductnewsaccurately,butcannotassume responsibility for the validity of product claims, or for typographical errors. The publishers also do not assume responsibility for product names or claims,orstatementsmadebyadvertisers.Opinions expressed by authors are their own and may not reflect those of DentalTribune International. Scan this code to subscribe our weekly Dental Tribune UK e-newsletter. By DTI LONDON & SOUTHAMPTON, UK: A number of studies have demon- strated that poor oral hygiene, a common problem among elderly patients, is a risk factor for devel- oping Alzheimer’s disease. Now, a joint research project led by scientists at the University of Southampton and King’s College London has provided further evi- dencethatperiodontitiscouldbeas- sociated with increased dementia severityandamorerapidcognitive decline in Alzheimer’s patients. Fifty-nine non-smoking pa- tients with an average age of 77.7, mild to moderate dementia and a minimum of ten teeth who had not received treatment for peri- odontitis in the past six months participated in the study. The pa- tients underwent dental exami- nations by a dental hygienist at baseline and at the six-month follow-up. In addition, blood samples were taken to measure inflammatory markers in their blood. The presence of periodontal diseaseatbaselinewasassociated with a sixfold increase in the rate of cognitive decline in partici- pants over the study period. Peri- odontitis at baseline was also as- sociated with a relative increase in the pro-inflammatory state over the follow-up period. Theresearchersconcludedthat periodontal disease is associated with an increase in cognitive decline in Alzheimer’s disease, possibly via mechanisms linked to the body’s inflammatory re- sponse. As the study only included a limited number of participants, the authors stated that the find- ings should be validated in a larger-cohort study. In addition, they highlighted that the precise mechanisms by which periodon- titis may be linked to cognitive decline are not fully understood and other factors might also play a part in the decline seen in par- ticipants’ cognition alongside their oral health. However, the current evidence is sufficient to explorewhetherperiodontaltreat- mentmightbenefitthetreatment of dementia and Alzheimer’s dis- ease, they said. Periodontitis is a common dis- ease in older people. The World Health Organization estimates that 15–20 per cent of adults aged 35–44 worldwide have severe periodontal disease. The condi- tion may become more common in Alzheimer’s disease because of a reduced ability to take care of oral hygiene as the disease progresses. Higher levels of antibodies to periodontal bacteria are asso- ciated with an increase in lev- els of inflammatory molecules elsewhere in the body, which in turn has been linked to greater rates of cognitive decline in Alzheimer’s disease in previous studies. Dr Mark Ide, from King’s Col- lege London Dental Institute and first author on the paper, said: “Gum disease is widespread in the UK and US, and in older age groups is thought to be a major cause of tooth loss. In the UK in 2009, around 80 per cent of adults over 55 had evidence of periodontal disease, while 40 per cent of adults aged 65–74 and 60 per cent of those older than 75hadlessthan21oftheiroriginal 32 teeth, with half of them report- ing periodontitis before they lost teeth.” The study, titled “Periodon- titis and cognitive decline in Alzheimer’s disease”, was pub- lished online on 10 March in the PLOS ONE journal. Periodontitis:Fastercognitive declineinpeoplewithAlzheimer’s ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providersof continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry. 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