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implants_international magazine of oral implantology No. 1, 2016

491 2016 implants New coating to Improve implants Hello from The Dentist’s side Big Data tool to Test new medicines Prebiotic compounds, whose origin can be ­traced back billions of years, have been studied intensively since their discovery several years ago. Now, a team of researchers in Australia has found that these prehistoric molecules can be used to modify surfaces of medical implants, reducing the risk of infection and rejection. The new coating method was developed by the Commonwealth Scientific and Industrial Re­- search Organisation (CSIRO) in collaboration with microbiologists at Monash University. They found that this polymerisation, carried out in buffered aqueous solutions, can be used to coat a wide range of organic and inorganic sub­ strate materials. The coating is biofriendly and cells readily grow on and colonise it and could therefore be applied to medical devices, such as dental implants, catheters and pacemakers to improve their performance and acceptance by the body, according to the researchers. “The non-toxic coating is adhesive and will coat almost all material, making its poten­tial biomedical applications really broad,” said lead research Dr Richard Evans. “This research opens the door to a host of new biomedical ­possibilities that are yet to be explored.” As the coating pro­ cess is very simple and uses ­methods and sub­ stances that are already available, biomedical manufacturers can produce improved results more cost effectively compared with existing techniques. The study, titled “Prebiotic-chemistry inspired polymer coatings for biomedical and material science applications”, was published online on 13 November in the NPG Asia Materials journal. Hardly ever is a visit at the dentist’s seen as a fun event. While many are aware of the patient’s side, only few take into account the dentist’s view. A dental clinic from Houston, Texas, now endeavors to overcome this bias by a very special music video: they have adapted Adele’s super hit “Hello” in favour of dentists worldwide. Friendly reminders remaining unheard, mis­ sed check-up appointments and the omni­ present danger of being bitten—as most people are usually seated on rather than in front of the dental chair, taking the dentist’s perspective is difficult. The den­ tal clinics New Teeth Dental Side has now turned the tables by recording a new version of Adele’s “Hello”, which features all aspects of the daily dental practice. The result is a funny parody which illuminates the special relation­ ship between dentist and patient. The following video recent­ ly went viral as it illustrates how dental fear impacts both patient and dentist: Australian scientists have developed a tool to map the effects of new medicines already on the market, potentially saving millions of health practitioners from prescribing medicines with lesser-known yet serious side effects. Lead re­ searcher Dr Nicole Pratt, a senior research fellow at the University of South Australia's School of Pharmacy and Medical Sciences, has been wor­ king with the Asian Pharmacoepidemiolo­ gy Network (AsPEN) to develop a mathe­ matical algorithm that charts the temporal relationship between a new medicine and reports of adverse side effects around the globe. The rapid detection tool is able to quickly analyse large population datasets of up to 200 million people, containing informa­tion about the time a patient is pre­ scribed a new medicine (captured at the point of purchase) and recorded hospitali­ sation events. “We look at the link between start­ing a new medicine and a hospitalisa­ tion event and determine whether there is an association between those two events”, said Pratt. At the time a new medicine is first released onto the market less than 50 per cent of the side effects are known. Source: www.theleadsouthaustralia.com.au [Picture:©KostenkoMaxim] [Picture:©3dfoto] 4912016

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