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I 49implants4_2015 AnarticleinthecurrentissueoftheJournalofOralIm- plantologydescribesasimplemethodtorecreatewhat isknownasthemouth’s“emergenceprofile”withim- plants. It presents step-by-step procedures that the authors used successfully in the clinic and laboratory for50implants. The current study looks at 50 cases of implants with customabutmentsmadeoftitaniumandzirconia,two commonlyusedmaterials.Abutmentsconnectthere- placementtoothtothebodyoftheimplant.Customis- ingtheirdesignallowssurgeonstocreateamorenat- uraltooth-emergenceprofileforeachpatient. The simple computerised technique provided a pre- cisefit,anditwaslessexpensiveandhadbetteraccu- racy than conventional techniques. To replicate their success, they noted that the process should be well planned before surgery and the implants should be placedaccurately.Inaddition,thesurgeonneedstobe careful when working with the soft tissue in the pa- tient’smouthandinserttemporarycrownsproperly.All implants were in place and had healed well one year later,withnosignsofirritationorinflammation.Allpa- tientsweresatisfiedwithhowtheimplantslooked.Full text of the article“Esthetic Considerations for Recon- structing Implant Emergence Profile Using Titanium and Zirconia Custom Implant Abutments: Fifty Case Series Report,”is available in the October issue of the JournalofOralImplantology. Computers Help Dental Implants Look Natural Researchers at University Medical Center (UMC) Utrecht have identified a gene that may cause oligodontia,theagenesisofsixormoreteeth.Thedis- covery of the so-called LPR6 gene makes it possible todiagnosepatientsmoreeffectively,pro- vide them with better information and develop customised treat- ment. Oligodontia is a rare but serious congen- italanomalydefinedbythe absence of six or more per- manent teeth.Children usually developmilkteethatayoungage, but when their permanent teeth start to erupt, it becomes clear that something is wrong. In several places, no adult teeth come in. In Europe, this condition affects 14 out of every 10,000 people. At the Center of Excellence in Congenital Oro- facial and Dental Anomalies, housed at UMCUtrecht,dentists,oralsurgeons,plas- tic surgeons and orthodontists collabo- rate in a multidisciplinary setting with clinicalgeneticistsoftheDepartmentof Medical Genetics. During a single visit, dental prob- lems are assessed, the patient—and/or parents— aregivenanexplanationofDNAresearchandarepre- sented with the offer to use it.Based on the findings ofthedentistandclinicalgeneticist,specific genetic research is possible. Van den Boogaard adds,“Most patients want to know the cause.Why does it develop? Willmychildrengetitaswell?Andwhatis theriskofthishappening?Thisnewresearch provides better insight into the biology of tooth development.The LPR6 gene is now included in the DNA diagnostics of oligodontia, en- ablingustogivepatientsabetterdiagno- sis, and to provide better information andtodevelopcustomizedtreatment.” Reference: Massink MPG, Créton MA, Spanevello F, et al. Loss-of-Function Muta- tions in the WNT co-receptor LRP6 Cause Autosomal-Domi- nant Oligodontia,TheAmerican Journal of Human Genetics,in press 2015. UMC Utrecht discovers genetic cause of Disturbed dental development Anexaminationof100biologicallyfaileddentalim- plantshasfoundthatmorethan60percentofthese implants showed signs of mechanical flaws, such as crack-like defects and full cracks. In publicising these results,the researchers aim to encouragedentalimplantmanufacturersandden- tists to find ways to reduce the structural damage thatoccurswhenametalissubjecttorepeatedap- plied loads. In the study, the researchers examined 100 dis- carded dental implants,which had been extracted owing to peri-implantitis, made of a titanium alloy and commercially pure titanium using energy dis- persive X-ray analysis and scanning electron mi- croscopy. Theyfoundmechanicaldefectsin62percentofthe specimens.Inaddition,theinspectionshowedthat the pure titanium implants had more cracks than did the titanium alloy implants. It was also found that the width and length of the different implants in this study were not correlated with the observed defects. Shemtov-Yona is now aiming to conduct further studies to investigate the reasons for the develop- mentofcrackstodeterminewhetherthecauseslie in manufacturing,use or both.The study,titled“On the mechanical integrity of retrieved dental im- plants”, was published in the September issue Journal of the Mechanical Behavior of Biomedical Materials. Study suggests many dental Implants may be prone to fracture [PICTURES: ©LHF GRAPHICS; VALDIS TORMS] [PICTURE: ©REDD_PANDDA] [PICTURE: ©ANDREY_POPOV]