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implants - international magazine of oral implantology

research I tional standardised and validated processing.11 Since 1985, over 250.000 PES-sterilized allogeneic bone grafts of the DIZG have been transplanted. Since to- day, there has been no report about transmission of disease or immunologic response. PESsterilisationforboneregeneration Regardingbiologicproperties,thegraftsshowos- teoconductive as well as osteoinductive characteris- tics. Various studies report unanimously that PES sterilization shows no significant effects on reduc- tion of osteoinductive properties on allogeneic bone grafts.23-26 After PES-sterilisation, following growth factors are detectable amongst others: BMP-2, BMP-4, IGF-1, TGF-ß1, VEGF and PDGF.26 It is well known that these growth factors have the ability to promoteboneregeneration.27 Additionally,thereisno limitation regarding procurement. Any quantity and qualitycaneffortlesslybeacquired.Figure4showsan example of the amount that is possible in augmenta- tion. It is doubtable that such results can be econom- ically managed with autogenous bone or other bone substitutes.Thecostsarerelativelylowandtherefore such grafting results are reasonable, establishing a situation for an uncompromising, prosthetic-based implant placement. Also, grafts have a shelf-life of five years. Caseoffailuresurgery Onegraftwaslostandremovedinsecondsurgery. It is unlikely that immunologic response or transmis- sionofdiseasewasreasonforlossofgraft.Inthiscase a bilateral sinus floor augmentation was performed and only one side caused problems. Figure 4 shows Table 1_Patients, follow-up and complications. m = male f = female Healing time = time between augmentation and implantation in months Follow-Up A = Follow-up in months after augmentation Follow-Up I = Follow-up in months after implantation I 17implants2_2014 Patient Sex Date of birth Age Compli- cation Augmentation date Implants installed Implantation date Healing time Follow- upA Follow- up B 1 f 29.07.1957 53 no 23.02.2010 yes 23.08.2010 6 12 6 2 m 08.09.1955 55 no 19.02.2009 yes 09.11.2009 8 24 15 3 f 30.12.1956 54 no 12.02.2010 yes 08.10.2010 7 12 4 4 m 23.10.1937 73 Graft lost 30.05.2009 no *** *** *** *** 5 f 02.12.1976 34 no 01.07.2010 yes 28.01.2011 6 7 1 6 f 19.08.1987 23 no 20.07.2009 yes 18.01.2010 5 19 13 7 m 08.07.1953 57 no 15.09.2009 yes 23.02.2010 5 17 12 8 f 05.09.1959 51 no 07.01.2010 yes 20.11.2010 10 13 3 9 m 15.06.1951 59 no 23.11.2009 yes 05.08.2010 8 15 6 10 f 11.12.1955 55 no 07.11.2008 yes 17.12.2009 13 27 14 11 f 15.08.1950 60 no 06.05.2009 yes 15.12.2009 7 21 14 12 m 11.01.1958 53 no 20.01.2009 yes 01.09.2009 7 25 17 13 m 26.12.1957 53 no 10.12.2008 yes 17.06.2009 6 26 20 14 f 16.04.1951 59 no 07.07.2008 yes 03.02.2009 6 31 24 15 f 05.03.1945 65 no 13.07.2009 yes 06.07.2010 11 19 7 16 m 10.02.1969 42 no 17.03.2009 yes 21.09.2009 6 23 17 17 f 28.04.1943 67 no 29.09.2008 yes 23.02.2009 4 28 24 18 f 17.02.1956 55 no 01.09.2009 yes,alio loco *** *** 17 *** 19 f 12.05.1947 63 no 21.12.2009 yes,alio loco *** *** 14 *** 20 m 24.02.1967 44 no 26.10.2010 yes,alio loco *** *** 4 *** 21 m 18.09.1932 78 no 14.05.2009 yes 18.11.2009 6 21 15 22 m 28.09.1969 41 no 12.03.2009 yes 03.08.2009 4 23 18 23 f 22.11.1952 58 no 22.07.2010 yes 24.01.2011 6 7 1 24 f 26.10.1952 58 no 14.03.2009 yes 08.08.2009 4 23 18 25 m 06.07.1949 61 no 18.05.2009 yes 21.10.2010 17 21 4 26 f 17.02.1943 68 no 08.07.2008 yes 02.02.2009 6 31 24 27 m 19.04.1954 56 no 12.11.2009 yes 01.09.2010 9 15 5 28 m 10.10.1961 49 no 08.05.2009 yes,alio loco *** *** 21 *** 29 f 25.10.1950 60 no 15.09.2009 yes,alio loco *** *** 17 *** 30 f 03.02.1978 33 no 01.12.2009 yes,alio loco *** *** 14 *** 31 m 01.05.1968 42 no 09.09.2009 yes 22.02.2010 5 17 12 32 m 27.01.1964 47 no 24.02.2009 yes 22.06.2010 15 24 8 33 f 24.02.1963 43 no 30.11.2009 yes 30.11.2010 12 14 2 34 m 24.12.1952 58 no 09.12.2009 yes,alio loco *** *** 14 *** 35 f 04.11.1957 53 no 25.02.2010 yes 08.10.2010 7 12 4 36 m 26.06.1947 63 no 21.04.2010 yes 08.12.2010 7 10 2

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