Dental Tribune Middle East & Africa Edition

5 µm 5 µm 5 µm Presenting advanced NovaMin® technology Sensodyne Repair & Protect is the first toothpaste to harness the advanced reparative power of NovaMin® plus fluoride. Originally developed for bone regeneration,1 NovaMin® delivers calcium and phosphate into your patient’s saliva2-4 and provides favourable conditions for hydroxyapatite-like layer formation. Building a reparative layer From as quickly as the first use,5 in vitro studies have shown a hydroxyapatite-like layer forming over exposed dentine and within the dentine tubules2,5-8 that is 50% harder than dentine.9 Introducing Sensodyne Repair & Protect Building a new layer of protection Building an integrated and resilient layer The hydroxyapatite-like layer formed binds firmly to the collagen in the patients dentine8,11 and helps protect your patients from the chemical and physical oral challenges they encounter in their everyday lives.6,9,10,12 In vitro studies have shown that the robust layer builds up over 5 days10 and, with twice-daily brushing, provides patients with continual protection from dentine hypersensitivity.13–15 Pre-brushing Post-brushing Post-acidic challenge Think beyond pain relief and recommend Sensodyne Repair & Protect In vitro SEM images of the tooth surface pre-brushing, of a reparative layer formed after twice-daily brushing for 4 days and of a reparative layer post a 5-minute acidic challenge.10 1. Greenspan DC. J Clin Dent 2010; 21(Spec Iss): 61–65. 2. LaTorre G, Greenspan DC. J Clin Dent 2010; 21(3): 72-76. 3. Edgar WM. Br Dent J 1992; 172(8): 305-312. 4. Arcos D et al. A J Biomed Mater Res 2003; 65: 344-351. 5. Earl J et al. J Clin Dent 2011; 22(Spec Iss): 62-67. 6. Burwell A et al. J Clin Dent 2010; 21(Spec Iss): 66–71. 7. West NX et al. J Clin Dent 2011; 22(Spec Iss): 82-89. 8. Efflandt SE et al. J Mater Sci Mater Med 2002; 26(6): 557-565. 9. Parkinson C et al. J Clin Dent 2011; 22(Spec Issue): 74-81. 10. Earl J et al. J Clin Dent 2011; 22(Spec Iss): 68-73. 11. Zhong JP et al. The kinetics of bioactive ceramics part VII: Binding of collagen to hydroxyapatite and bioactive glass. In Bioceramics 7, (eds) OH Andersson, R-P Happonen, A Yli-Urpo, Butterworth-Heinemann, London, pp61–66. 12. Wang Z et al. J Dent 2010; 38: 400−410. 13. Salian S et al. J Clin Dent 2010; 21(3): 82-87. 14. Du MQ et al. Am J Dent 2008; 21(4): 210−214. 15. Pradeep AR et al. J Periodontol 2010; 81(8): 1167−1113. Prepared December 2011, Z-11-517. OH/CA/01/13/001