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Dental Tribune United Kingdom Edition

R esearchers from the uni- versities of Granada and Murcia have confirmed the effectiveness of a spray contain- ing one per cent malic acid, which greatly improves xerostomia, or dry mouth, caused by anti-depres- sant drugs. As the main author of this study, University of Granada lec- turer, Gerardo Gomez Moreno, explains, one of the main causes of dry mouth is the consumption of different medications. “There are over 500 drugs, belonging to 42 pharmacological groups, which can provoke xerostomy as a side effect. Those that are most related are anti-depressants, the prescription of which has in- creased over recent years, thus leading to a higher number of pa- tients with xerostomy from taking anti-depressive drugs, above all in 45-50 year olds”. The University of Granada research was carried out in a double-blind randomised clinical trial on 70 patients diagnosed with anti-depressant-induced xeros- tomy, split into two groups. The first group of 35 patients took a sialogogue mouth spray (one per cent malic acid), while the sec- ond group - also consisting of 35 patients - received a placebo. Both products were applied on demand over two weeks. To check the xe- rostomy both before and after ap- plying both the product and the placebo, the researchers used a specific questionnaire, called the Dry Mouth Questionnaire (DMQ). Dr. Gomez Moreno points out that are various therapeutic pos- sibilities for treating xerostomy (sialogogues, salivary substitutes, other general treatments), “al- though the effectiveness of many of them is controversial. For ex- ample, some studies have de- scribed citric and malic acid as salivary stimulants, even though, for years, their use was rejected due to the possible de-mineralis- ing effect on tooth enamel”. The results have been pub- lished in the latest edition of the Official American Journal on De- pression and Anxiety. DT Spray treats dry mouth caused by anti-depressants H ello and wel- come to the brave new world that is life un- der the authority of the NHS Commissioning Board, or NHS England as they are now officially and affectionately known. A look at the auspicious who’s who of the management board on the NHS England web- site includes people from all over the medical and manage- ment spectrum… except den- tistry! In fact the visibility given to the fact that they are now commissioning dental services is such that it is actually not that easy to find anything about the sector on the site. I hope this is not a sign of things to come… As a team we are looking for- ward to the upcoming BDA Con- ference and Exhibition. I always enjoythisevent,it’sgreattocatch up with colleagues and update on the latest news and views surrounding the profession. I’m really interested to gauge the reaction from BDA members over the new membership structure – I am sure that this will be one of the topics to be discussed by the coffee machines! DT Do you have an opinion or some- thing to say on any Dental Tribune UK article? Or would you like to write your own opinion for our guest comment page? If so don’t hesitate to write to: The Editor, Dental Tribune UK Ltd, 4th Floor, Treasure House, 19-21 Hatton Garden, London, EC1 8BA Or email: lisa@healthcare-learning.com Editorial comment United Kingdom Edition April 15-21, 2013 3News