Dental Tribune United Kingdom Edition

February 25- March 3, 201322 Perio Tribune United Kingdom Edition bial substances). Indirect interactions may include13 : 1 Modulating systemic im- mune function effect on local im- munity 2Effect on non- immunologic defence mechanisms 3Regulation of mucosal per- meability 4 Selection pressure on de- veloping oral microflora towards colonisation by less pathogenic species. There is scientific evidence that certain strains of probiotic microorganisms confer benefits to the health of the host and are safe for human use. However fur- ther research is required to affirm benefits of probiotics. There exists a connection be- tween diet and health, including oral health. The mechanisms of action of probiotics in the com- plex interplay in developing and developed microbial colonies and oral biofilms are also not known. Randomised controlled trials are needed to assess the best means of administering probiotics and the dosages needed for different pre- ventive or therapeutic purposes. We also know little about the possible naturally occurring resident probiotics of the mouth. Further research is needed to determine how various probiot- ics strains are able to prevent the growth of oral microorganisms other than the caries pathogens and Candida investigated to date. Bacteriotherapy in the form of probiotics seems to be a new al- ternative for oral health giving a new research field for dental sci- ence to proceed. DT Concentrated Effective Safe I Each super-concentrated 8ml cartridge of Virofex makes 500ml of working solution. I The lightweight cartridge refill pack is equivalent to a heavy, cumbersome 5L container of conventional disinfectant – and it can be wall-mounted. I Virofex is highly effective against bacteria, fungi, TB, viruses and spores; including MRSA, C-Diff, HIV, Hepatitis and RotaVirus. I Tests have shown that, even after 24 hours, surfaces sprayed with Virofex have a high resistance to contaminating organisms. I Even the dispenser pack itself is bactericidal! I Virofex is compatible with all surfaces and material types – eliminating the need for different solutions. I Alcohol-free and non-flammable, Virofex does not smell of harmful biocides. Heavyweight Disinfection (Just add water) Available exclusively in the UK from The Dental Directory and Topdental For more information on this innovative new product, call 01535 652 750 or email sales@virofex.com Alternatively, watch our demonstration video on YouTube. www.virofex.com Fill the system bottle with 500ml of clean cold water, place one cartridge into the neck of the bottle and replace trigger spray. Gently shake the bottle for a few seconds prior to use. Virofex will remain active for 12 months following activation. Introducing Virofex,™ an innovative alcohol-free high level surface disinfection system for use on non-invasive medical devices. Simply add 500ml of tap water to the system bottle, put one Virofex cartridge into the neck, replace the trigger, shake for a few seconds and it’s ready! Fresh, perfect strength working solution every time, without any spill hazard or the need for cumbersome and dangerous 5 litre refill containers. www.topdental.co.uk 01535 652 750 Call 0800 585 586 Virofex A3 Advert - Tribune_Layout 1 22/01/2013 16:15 Page 1 page 21DTß References: 1. Teughel S, Essche MV, Sliepen I and Quirynen M. Probiotics in oral health care: Periodontology 2000,2008; 48: 111-147 2. Schrezenmeir J, de Vrese M. Probiot- ics, prebiotics, and synbiotics: approach- ing a definition. Am J Clin Nutr 2001; 73: 361s – 364s. 3. Wilson M. Manipulation of the indigenous microbiotia. In : Wilson M, editors. Microbial inhabitants of humans. Newyork: Cambridge University Press, 2005: 395-416. 4. Sanders M E. Probiotics: A publication of the institute of food tech- nologists. Expert panel on food safety and nutrition. 1999; 53 (11): 67-77. 5. Orrhaje K, Brismar B, Nord C E. Effect of supple- ments with bifido bacterium longum and lactobacillus acidophilus on the intestinal microbiota during administration of clin- damycin. Microb Ecol health dis 1994; 7: 1722. 6. Lilly D M, Stillwell R H. Probiotics: Growth promoting factors produced by mi- cro organisms. Science 1965; 147: 747-748. 7. Lidback, A., Nord, C E, Rafter, J., Nord, C. Gustaffson, J.A. Effect of lactobacillus acidophilus supplements on mutagen excre- tion in faeces and urine in humans. Micrb Ecol health dis 1992; 5: 59-67. 8. Saxelin N, lactobacillus GG. A human probiotic strain with thorough clinical documenta- tion. Food Rev Int 1997; 13: 293-313. 9. Cohen P S, Laux DC, Bacterial adhesion to and penetration of intestinal mucous in vitro. Methods Enzymol 1995; 253: 309-314. 10. Collins JK, Murphy L, Omahony L, A control trial of probiotic bacteria on can- didiasis in immune deficient mice. Infect im- mune 1997; 65: 4165-4172 11. Wagener RD, Warner T, Roberts L, Farmer J, Coloniza- tion of congenitally immune deficient mice with probiotic bacteria. Infect immuo 1997; 3345-3351. 12. Kato I, Yokura T, Mutai M. Macrophage activation by lactobacillus Casei in mice. Micro immune 1983; 27: 611- 618. 13. Meurman JH. Probiotics: Do they have role in oral medicine and dentistry? Eur J Oral Sci; 2005; 113: 188-196. 14. Noordin K, Kamin S. The effect of probiot- ics mouth rinse on plaque and gingival in- flammation. Anal Dent University, Malaya. 2007; 14: 19-25. 15. Shimauchi H, Mayan- agi Gen et al. Improvement of periodontal condition by probiotics with lactobacillus salivarius WB21: Randomized, double blind, placebo controlled study, J Clin Peri- odontol 2008; 35: 897-905. 16. Kang MS, Kim BG, Lee HC, Oh JS. Inhibitory effect of Weissella cibaria on the production of vola- tile sulphur compounds. J Clin Periodontol 2006; 33: 226-232. 17. Burton JP, Chilcoot CN,Tagg JR. The rationale and potential for the reduction of oral malodor using streptococcus salivarius probiotics. Oral diseases 2005; 11 (suppl 1): 29-31. 18. Kang MS, Na HS, Oh LS. Coaggregation ability of Weissella cibaria isolates with Fusobac- terium nucleatum and their adhesiveness to epithelial cells. FEMS Microbiol Lett, 2005; 253: 323-329. 19. Volozhin AI, Il‘in VK, Maksimovskii IM et al . Development and use of periodontal dressing of collagen and Lactobacillus casei 37 cell suspension in combined treatment of periodontal disease of inflammatory origin (a microbiologi- cal study). Stomatologiia (Mosk) 2004; 83: 6–8. 20. Koll-Klais P, Mandar R, Leibur E, Marcotte H, Hammarstrom L, Mikelsaar M . Oral lactobacilli in chronic periodontitis: species composition and antimicrobial ac- tivity. IADR Congress, Dublin,2006; 13–16 September (Abstract 0081). 21. Elahi S, Pang G, Clancy A, Clancy R . Enhanced clearance of Candida albicans from the oral cavities of mice following oral admin- istration of Lactobacillus acidophilus.Clin Exp Immunol 2005; 141: 29–36. 22. Caglar E, Cilder SK, Ergeneli S, Sandalli N, Twet- man S . Salivary mutans streptococci and lactobacilli levels after ingestion of the probiotic bacterium Lactobacillus reuteri ATCC 55739 by straws or tablets. Acta Od- ontol Scand. 2006; 64: 314–318. 23. Turner SR, Love RM, Lyons KM. An in-vitro inves- tigation of the antibacterial effect of nisin in root canals and canal wall radicular den- tin. International Endodontic Journal 2004; 37: 664-71. About the author Dr.Rahul Kale, MDS Senior Lecturer Dept of Periodontology and Implan- tology, M.A.Rangoonwala College of Dental Sciences and Research Centre, Pune, India E-mail: dr.rahul_dkale@yahoo.com