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molar and second premolar mesially to close the anteriorspace.Thiswouldopenupenoughspace to replace the missing lower right molar with an implant. Treatment progress The patient used 19 aligners for two weeks each.Theentiretreatmenttimewasninemonths and two weeks. The movements achieved are shown in Table I. Results Upon final treatment, the anterior spaces had been completely closed and space had been created to replace the missing lower right first molar with an implant (Fig. 3). _Case II: Space management for a congenitally missing tooth Diagnosis A 32-year-old male patient reported to my clinic with spaces between his upper teeth and forwardly placed incisors. The patient was diagnosed with a Class I mal- occlusion with a missing upper right lateral in- cisor, spacing in the upper arch, proclined upper and lower incisors, a midline shift owing to de- viation of the upper midline 1 mm to the right side, and higher upper labial frenum attachment (Fig. 4). Treatment objectives The treatment objectives were: 1. maintenance of the Class I molar and canine relationship; 2. creation of adequate space for the missing upper right lateral incisor; 3. closure of any other spaces in the upper arch; 4. midline correction; and 5. retroclination of the upper and lower incisors. Fig. 6d Fig. 6e Fig. 6f Fig. 6a Fig. 6b Fig. 6c Fig. 4f Fig. 4g Fig. 4h Fig. 4a Fig. 4b Fig. 4c Fig. 4d Fig. 4e Fig. 5 Table II I 31CAD/CAM 2_2012 case report _ CAD/CAM aligners I Table II_Teeth movement records for case 2.